CA IX-IN-5
CA IX-IN-5 (compound 9) is a human carbonic anhydrase IX (hCA IX) inhibitor with a Ki of 7.4 nM against hCA IX and 25.0 nM against hCA II.CA IX-IN-5 functionally inhibits hCA IX and hCA II isoenzymes, with selectivity for hCA IX over hCA II.CA IX-IN-5 can be used for the research of breast, colorectal, glioblastoma, lung, head and neck, and cervical cancers.
Nur für Forschungszwecke. Wir verkaufen nicht an Patienten.
- Formel: C20H23ClN6O5S
- Molecular Weight:494.95
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
CA IX-IN-5 (compound 9) (0.05-50 μM; 10 min) potently inhibits human carbonic anhydrase IX (Ki = 7.4 nM) with 3.4-fold selectivity over human carbonic anhydrase II[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Molecular Weight 494.95
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Formel C20H23ClN6O5S
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SMILES
COC1=CC(NC2=NC(NCCC3=CC=C(C=C3)S(=O)(N)=O)=NC(Cl)=N2)=CC(OC)=C1OC
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)