JAK2-IN-17
JAK2-IN-17 (compound 20) is a potent JAK2 allosteric inhibitor. JAK2-IN-17 inhibits full-length JAK2 and JAK2 V617F with IC50s of 160 and 130 nM, respectively. JAK2-IN-17 covalently modifies Lys677 in the pseudokinase domain.
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- Formel: C15H13FN6O6S2
- Molecular Weight:456.43
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
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FL JAK2 wt 160 nM (IC50) |
FL JAK2 V617F 130 nM (IC50) |
Chemical Information
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Molecular Weight 456.43
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Formel C15H13FN6O6S2
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SMILES
NS(C1=CC=C(NC2=NN(C(C3=CC=CC(OS(F)(=O)=O)=C3)=O)C(N)=N2)C=C1)(=O)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
JAK2-IN-17 Related Classifications
HY-179428 Related Classifications
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