IWP-2-V2
Based on 1 Customer Validation
IWP-2-V2 is a IWP-2 (HY-13912) analogue that retains activity against the Wnt/β-catenin pathway.
For research use only. We do not sell to patients.
- Purity: 98.39%
- CAS No.: 877618-79-6
- Formula: C23H20N4O2S3
- Molecular Weight:480.63
-
Storage:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
|
Cell Line
|
Type | Value | Description | References |
|---|---|---|---|---|
| CAPAN-1 | EC50 |
>10 μM
Compound: IWP-2-V2
|
Antiproliferative activity against human Capan1 cells after 48 hrs by MTT assay
Antiproliferative activity against human Capan1 cells after 48 hrs by MTT assay
|
[PMID: 29630366] |
| HEK293 | EC50 |
>10 μM
Compound: IWP-2-V2
|
Antiproliferative activity against human HEK293 cells after 48 hrs by MTT assay
Antiproliferative activity against human HEK293 cells after 48 hrs by MTT assay
|
[PMID: 29630366] |
| HT-29 | EC50 |
>10 μM
Compound: IWP-2-V2
|
Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay
Antiproliferative activity against human HT-29 cells after 48 hrs by MTT assay
|
[PMID: 29630366] |
| MIA PaCa-2 | EC50 |
5.65 μM
Compound: IWP-2-V2
|
Antiproliferative activity against human MIAPaCa2 cells after 48 hrs by MTT assay
Antiproliferative activity against human MIAPaCa2 cells after 48 hrs by MTT assay
|
[PMID: 29630366] |
| PANC-1 | EC50 |
>10 μM
Compound: IWP-2-V2
|
Antiproliferative activity against human PANC1 cells after 48 hrs by MTT assay
Antiproliferative activity against human PANC1 cells after 48 hrs by MTT assay
|
[PMID: 29630366] |
| SW-620 | EC50 |
8.52 μM
Compound: IWP-2-V2
|
Antiproliferative activity against human SW620 cells after 48 hrs by MTT assay
Antiproliferative activity against human SW620 cells after 48 hrs by MTT assay
|
[PMID: 29630366] |
Chemical Information
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CAS No. 877618-79-6
-
Appearance Solid
-
Molecular Weight 480.63
-
Formula C23H20N4O2S3
-
SMILES
O=C(NC1=NC2=C(S1)C=C(C=C2)C)CSC(N3CC4=CC=CC=C4)=NC5=C(C3=O)SCC5
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)