(1R)-AZD-1480
Based on 1 Customer Validation
(1R)-AZD-1480 is the (1R) chiral isomer of AZD-1480, an ATP competitive JAK1 and JAK2 inhibitor.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 97.62%
- CAS No.: 935666-99-2
- Formule: C14H14ClFN8
- Masse moléculaire:348.77
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Stockage:
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
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Solvant et solubilité
- Pureté et documentation
- Références
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Help & FAQs
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Bioactive Compound Library Max
HY-L181
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Bioactive Compound Library
HY-L001
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Epigenetics Compound Library
HY-L005
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Immunology/Inflammation Compound Library
HY-L007
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JAK/STAT Compound Library
HY-L008
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Kinase Inhibitor Library
HY-L009
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Protein Tyrosine Kinase Compound Library
HY-L016
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Stem Cell Signaling Compound Library
HY-L017
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Anti-Cancer Compound Library
HY-L025
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Anti-Aging Compound Library
HY-L034
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Differentiation Inducing Compound Library
HY-L038
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Reprogramming Compound Library
HY-L039
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Anti-Breast Cancer Compound Library
HY-L074
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Anti-Lung Cancer Compound Library
HY-L075
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Anti-Pancreatic Cancer Compound Library
HY-L077
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Anti-Blood Cancer Compound Library
HY-L079
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Anti-Obesity Compound Library
HY-L087
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Anti-Liver Cancer Compound Library
HY-L101
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Anti-Prostate Cancer Compound Library
HY-L124
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Cancer Stem Cells Compound Library
HY-L135
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Autoimmune Disease Compound Library
HY-L156
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Anti-Hematopathy Compound Library
HY-L171
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MCE Bioactive Compound Library
HY-L001V
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Protein Kinase Compound Library
HY-L196
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High-Throughput Bioactive Compound Library
HY-L205
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Anti-Rheumatic Arthritis Compound Library
HY-L210
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Posttranslational Modification Library
HY-L226
Activité biologique
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| BaF3 | GI50 |
11 μM
Compound: 21
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Growth inhibition of mouse BA/F3 cells expressing Tel-JAK2 kinase after 48 hrs by MTS assay
Growth inhibition of mouse BA/F3 cells expressing Tel-JAK2 kinase after 48 hrs by MTS assay
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[PMID: 21138246] |
Chemical Information
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CAS No. 935666-99-2
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Appearance Solid
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Masse moléculaire 348.77
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Formule C14H14ClFN8
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Color White to off-white
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SMILES
ClC1=C(N=C(N=C1)N[C@H](C)C2=NC=C(C=N2)F)NC3=NNC(C)=C3
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
4°C, protect from light
* In solvent : -80°C, 6 months; -20°C, 1 month (protect from light)
Solvant et solubilité
DMSO : 100 mg/mL (286.72 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
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Fiche technique (270 KB)
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SDS (392 KB)
- English - EN (392 KB)
- Français - FR (392 KB)
- Deutsch - DE (392 KB)
- Norwegian - NO (392 KB)
- Español - ES (392 KB)
- Swedish - SV (392 KB)
- Italian - IT (392 KB)
- Korean - KR (392 KB)
- Portuguese - PT (392 KB)
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Instruction de manipulation (2659 KB)
Références
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (protect from light). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.8672 mL | 14.3361 mL | 28.6722 mL | 71.6805 mL |
| 5 mM | 0.5734 mL | 2.8672 mL | 5.7344 mL | 14.3361 mL | |
| 10 mM | 0.2867 mL | 1.4336 mL | 2.8672 mL | 7.1680 mL | |
| 15 mM | 0.1911 mL | 0.9557 mL | 1.9115 mL | 4.7787 mL | |
| 20 mM | 0.1434 mL | 0.7168 mL | 1.4336 mL | 3.5840 mL | |
| 25 mM | 0.1147 mL | 0.5734 mL | 1.1469 mL | 2.8672 mL | |
| 30 mM | 0.0956 mL | 0.4779 mL | 0.9557 mL | 2.3893 mL | |
| 40 mM | 0.0717 mL | 0.3584 mL | 0.7168 mL | 1.7920 mL | |
| 50 mM | 0.0573 mL | 0.2867 mL | 0.5734 mL | 1.4336 mL | |
| 60 mM | 0.0478 mL | 0.2389 mL | 0.4779 mL | 1.1947 mL | |
| 80 mM | 0.0358 mL | 0.1792 mL | 0.3584 mL | 0.8960 mL | |
| 100 mM | 0.0287 mL | 0.1434 mL | 0.2867 mL | 0.7168 mL |
(1R)-AZD-1480 Related Classifications
HY-10193A Related Classifications
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