CA IX-IN-5
CA IX-IN-5 (compound 9) is a human carbonic anhydrase IX (hCA IX) inhibitor with a Ki of 7.4 nM against hCA IX and 25.0 nM against hCA II.CA IX-IN-5 functionally inhibits hCA IX and hCA II isoenzymes, with selectivity for hCA IX over hCA II.CA IX-IN-5 can be used for the research of breast, colorectal, glioblastoma, lung, head and neck, and cervical cancers.
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- Formule: C20H23ClN6O5S
- Masse moléculaire:494.95
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Activité biologique
CA IX-IN-5 (compound 9) (0.05-50 μM; 10 min) potently inhibits human carbonic anhydrase IX (Ki = 7.4 nM) with 3.4-fold selectivity over human carbonic anhydrase II[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 494.95
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Formule C20H23ClN6O5S
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SMILES
COC1=CC(NC2=NC(NCCC3=CC=C(C=C3)S(=O)(N)=O)=NC(Cl)=N2)=CC(OC)=C1OC
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)