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Cat. No.: HY-182086

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Copanlisib-NH

Copanlisib-NH is a PI3Kα/δ ligand. Copanlisib-NH can be used as a ligand for target protein for PROTAC to develop and design degraders of PROTAC PI3Kα/δ, such as PROTAC PI3Kα/δ degrader-1 (HY-182083). Copanlisib-NH can be used in breast cancer research.

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CAS No.: 2355277-02-8
Formule: C₂₃H₂₉N₉O₃
Masse moléculaire:479.53

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Copanlisib-NH Chemical Structure

CAS No.: 2355277-02-8

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Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références
Calculators
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Description

IC₅₀ & Targetsup>[1]

PI3Kα

PI3Kδ

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Chemical Information

CAS No. 2355277-02-8
Masse moléculaire 479.53
Formule C₂₃H₂₉N₉O₃
SMILES

NC(N=C1)=NC=C1C(NC(N2C3=NCC2)=NC4=C3C=CC(OCCCN5CCNCC5)=C4OC)=O
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Hou Y, et al. Rational Design of Potent and Orally Efficacious PI3Kα/δ Degrader for PIK3CA Mutant Breast Cancer without Hyperglycemic Liability. J Med Chem. Published online March 8, 2026. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
Chemical Information
Pureté et documentation
Références

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Copanlisib-NH

Voir tous les produits spécifiques à Isoform PI3K

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Copanlisib-NH Related Classifications

HY-182086 Related Classifications