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Cat. No.: HY-118537

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ICI 56780

ICI 56780 is an antimalarial agent, that exhibits etiological prevention and blood schizonticidal activity in rodent malaria models. ICI 56780 develops parasite resistance in P. berghei infected mice.

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CAS No.: 28130-28-1
Formule: C₂₃H₂₅NO₅
Masse moléculaire:395.45

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Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (264 KB)

ICI 56780 Chemical Structure

CAS No.: 28130-28-1

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- Cellular Effect
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Voir tous les produits spécifiques à Isoform Parasite :

Cellular Effect

Cell Line	Type	Value	Description	References
J774	EC₅₀	>20 μM Compound: 6b	Cytotoxicity against mouse J774 cells Cytotoxicity against mouse J774 cells	[PMID: 27291102]
J774	EC₅₀	46 μM Compound: 5, ICI-56780	Antiproliferative against mouse J774 cells after 72 hrs by Cell titer assay Antiproliferative against mouse J774 cells after 72 hrs by Cell titer assay	[PMID: 22111907]

Chemical Information

CAS No. 28130-28-1
Masse moléculaire 395.45
Formule C₂₃H₂₅NO₅
SMILES

O=C(C1=CNC2=CC(OCCOC3=CC=CC=C3)=C(CCCC)C=C2C1=O)OC
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (264 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Cross RM, et al., Synthesis, antimalarial activity, and structure-activity relationship of 7-(2-phenoxyethoxy)-4(1H)-quinolones. J Med Chem. 2011 Dec 22;54(24):8321-7. [Content Brief]

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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Activité biologique
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Chemical Information
Pureté et documentation
Références

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ICI 56780

Voir tous les produits spécifiques à Isoform Parasite

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

ICI 56780 Related Classifications

HY-118537 Related Classifications