NEU-5123
NEU-5123 is a human kinase inhibitor with potent inhibitory activity to several kinases. NEU-5123 is a Trypanosome proliferation inhibitor. NEU-5123 can be used for the research of infection.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Formule: C22H23N5
- Masse moléculaire:357.45
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Activité biologique
NEU-5123 (Compound 18a) potently inhibits Trypanosoma brucei proliferation (PEC50 = 7.7), exhibits low toxicity to human lung fibroblast MRC5 cells (PTC50 = 4.8) with a SI of 850[1].
NEU-5123 (5 μM) potently inhibits 14 human kinases (defined as >50% inhibition) in a panel of 45 human kinases[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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Masse moléculaire 357.45
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Formule C22H23N5
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SMILES
CN1C=C(C=N1)C2=C3C=C(NC3=NC=C2)C4=CC=C(C=C4)CN5CCCC5
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)