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Cat. No.: HY-182941

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Parawixin10

Parawixin10 (Compound 2) is an N-acylpolyamine. Parawixin10 fails to enhance glutamate uptake in radioligand uptake assays of EAAT1, EAAT2 or EAAT3. Parawixin10 exhibits no positive allosteric modulatory activity in radioligand uptake assays of EAAT1−EAAT3, nor can it improve neuronal survival rates in mice in a dose-dependent and statistically significant manner. Parawixin10 has no neuroprotective activity.

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Formule: C₃₀H₅₅I₂N₉O₃
Masse moléculaire:843.63

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Parawixin10 Chemical Structure

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
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Bioz

Activité biologique

Description

IC₅₀ & Target^[1]^[2]^[3]

EAAT1

EAAT2

EAAT3

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In Vitro

Parawixin10 (1 nM-10 μM; 10 min) exerts no regulatory effect on the uptake of [³H]-D-Asp or [³H]-L-Glu in HEK293 cells expressing EAAT1 and EAAT2^[1].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

Masse moléculaire 843.63
Formule C₃₀H₅₅I₂N₉O₃
SMILES

C[N+](C)(CCCC[N+](C)(C)CCCNC(CC1=CNC2=CC=CC(O)=C21)=O)CCCNC([C@H](CCCNC(N)=N)N)=O.[I-].[I-]
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Instruction de manipulation (2659 KB)

Références

[1]. Doroudian Y, et al. The N-Acylpolyamine Structure Assigned as Parawixin10 Does Not Display Positive Allosteric Modulatory Activity in EAAT1-3 Radioligand Uptake Assays, nor Does It Enhance Neuronal Survival in Mice in a Dose-Dependent and Statistically Significant Way. ACS Chem Neurosci. 2026;17(8):1530-1539. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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100 mg

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Activité biologique
- Description
- IC₅₀ & Target
- In Vitro
Chemical Information
Pureté et documentation
Références

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Parawixin10

Voir tous les produits spécifiques à Isoform EAAT

Activité biologique

Chemical Information

Pureté et documentation

Références

Calculators

Help & FAQs

Parawixin10 Related Classifications

HY-182941 Related Classifications