[Tyr8] Bradykinin
Based on 1 Customer Validation
[Tyr8] Bradykinin is a B2 kinin receptor agonist. [Tyr8] Bradykinin also stimulates ERK1/2 phosphorylation. [Tyr8] Bradykinin can be used as an internal standard.
Nos produits utilisent uniquement pour la recherche. Nous ne vendons pas aux patients.
- Pureté: 99.61%
- CAS No.: 32222-00-7
- Formule: C50H73N15O12
- Masse moléculaire:1076.21
-
Stockage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
![[Tyr8] Bradykinin Chemical Structure](https://file.medchemexpress.com/product_pic/hy-p3751.gif "Click to View [Tyr8] Bradykinin Chemical Structure")
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
-
Activité biologique
-
Chemical Information
-
Solvant et solubilité
- Pureté et documentation
- Références
-
Help & FAQs
Voir tous les produits spécifiques à Isoform Bradykinin Receptor
More
Activité biologique
|
ERK1 |
ERK2 |
[Tyr8] Bradykinin (10 nM, 2 min) produces a rapid increase in phosphorylated ERK1/2[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
-
Cell Line:Serum-deprived trabecular meshwork cells
-
Concentration:10 nM
-
Incubation Time:2 min
-
Result:Produced a rapid increase in phosphorylated ERK1/2 that was equivalent in magnitude to that observed for Bradykinin (HY-P0206).
Chemical Information
-
CAS No. 32222-00-7
-
Appearance Solid
-
Masse moléculaire 1076.21
-
Formule C50H73N15O12
-
Color White to off-white
-
Sequence Shortening
RPPGFSPYR
-
Livraison
Room temperature in continental US; may vary elsewhere.
-
Stockage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Solvant et solubilité
DMSO : 100 mg/mL (92.92 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Pureté et documentation
-
Fiche technique (282 KB)
-
SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
-
Instruction de manipulation (2659 KB)
Références
[1]. Webb JG, et al. Bradykinin activation of extracellular signal-regulated kinases in human trabecular meshwork cells. Exp Eye Res. 2011 Jun;92(6):495-501. [Content Brief]
[2]. Wilson SR, et al. Determination of bradykinin and arg-bradykinin in rat muscle tissue by microdialysis and capillary column-switching liquid chromatography with mass spectrometric detection. J Sep Sci. 2005 Sep;28(14):1751-8. [Content Brief]
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 0.9292 mL | 4.6459 mL | 9.2919 mL | 23.2297 mL |
| 5 mM | 0.1858 mL | 0.9292 mL | 1.8584 mL | 4.6459 mL | |
| 10 mM | 0.0929 mL | 0.4646 mL | 0.9292 mL | 2.3230 mL | |
| 15 mM | 0.0619 mL | 0.3097 mL | 0.6195 mL | 1.5486 mL | |
| 20 mM | 0.0465 mL | 0.2323 mL | 0.4646 mL | 1.1615 mL | |
| 25 mM | 0.0372 mL | 0.1858 mL | 0.3717 mL | 0.9292 mL | |
| 30 mM | 0.0310 mL | 0.1549 mL | 0.3097 mL | 0.7743 mL | |
| 40 mM | 0.0232 mL | 0.1161 mL | 0.2323 mL | 0.5807 mL | |
| 50 mM | 0.0186 mL | 0.0929 mL | 0.1858 mL | 0.4646 mL | |
| 60 mM | 0.0155 mL | 0.0774 mL | 0.1549 mL | 0.3872 mL | |
| 80 mM | 0.0116 mL | 0.0581 mL | 0.1161 mL | 0.2904 mL |
[Tyr8] Bradykinin Related Classifications
HY-P3751 Related Classifications
Powered by Bioz