Casein kinase 1δ-IN-1
Based on 1 Customer Validation
Casein kinase 1δ-IN-1 is an inhibitor of casein kinase 1δ (CK1δ). Casein kinase 1δ-IN-1 can be used for the research of neurodegenerative diseases such as tauopathies.
For research use only. We do not sell to patients.
- Purity: 99.91%
- CAS No.: 851871-94-8
- Formula: C11H7N3OS
- Molecular Weight:229.26
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
Biological Activity
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CK1δ |
Casein kinase 1δ-IN-1 (Compound 822) (20 μM; 120 min) inhibits CK1δ by more than 5%[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 851871-94-8
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Appearance Solid
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Molecular Weight 229.26
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Formula C11H7N3OS
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Color Off-white to light brown
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SMILES
O=C(C1=NC=CC=C1)NC2=C(C#N)C=CS2
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 41.67 mg/mL (181.76 mM; ultrasonic and warming and heat to 80°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (275 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 4.3619 mL | 21.8093 mL | 43.6186 mL | 109.0465 mL |
| 5 mM | 0.8724 mL | 4.3619 mL | 8.7237 mL | 21.8093 mL | |
| 10 mM | 0.4362 mL | 2.1809 mL | 4.3619 mL | 10.9047 mL | |
| 15 mM | 0.2908 mL | 1.4540 mL | 2.9079 mL | 7.2698 mL | |
| 20 mM | 0.2181 mL | 1.0905 mL | 2.1809 mL | 5.4523 mL | |
| 25 mM | 0.1745 mL | 0.8724 mL | 1.7447 mL | 4.3619 mL | |
| 30 mM | 0.1454 mL | 0.7270 mL | 1.4540 mL | 3.6349 mL | |
| 40 mM | 0.1090 mL | 0.5452 mL | 1.0905 mL | 2.7262 mL | |
| 50 mM | 0.0872 mL | 0.4362 mL | 0.8724 mL | 2.1809 mL | |
| 60 mM | 0.0727 mL | 0.3635 mL | 0.7270 mL | 1.8174 mL | |
| 80 mM | 0.0545 mL | 0.2726 mL | 0.5452 mL | 1.3631 mL | |
| 100 mM | 0.0436 mL | 0.2181 mL | 0.4362 mL | 1.0905 mL |