Epiblastin A
Based on 1 publication(s) in Google Scholar
Epiblastin A is an ATP competitive casein kinase 1 (CK1) inhibitor with IC50s of 8.9, 0.5, and 4.7 µM for CK1α, CK1δ, and CK1 ɛ, respectively. Epiblastin A induces reprogramming of epiblast stem cells into embryonic stem cells by inhibition of CK1.
연구목적의 판매만을 진행합니다. 환자를 대상으로 한 판매는 하지 않습니다.
- Purity: 99.44%
- CAS No.: 16470-02-3
- 화학식: C12H10ClN7
- 분자량:287.71
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보관:Powder -20°C, 3 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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용액&용해도
- 순도&문서
- References
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Help & FAQs
Publications Citing Use of MedChemExpress (MCE) Epiblastin A
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Biological Activity
Chemical Information
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CAS No. 16470-02-3
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Appearance Solid
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분자량 287.71
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화학식 C12H10ClN7
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Color Light yellow to green yellow
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SMILES
NC1=NC(N)=C2N=C(C(N)=NC2=N1)C3=CC=CC(Cl)=C3
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선적
Room temperature in continental US; may vary elsewhere.
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보관
Powder -20°C 3 years In solvent -80°C 6 months -20°C 1 month
Publications (1)
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Journal Impact Factor
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Most Recent
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J Clin Invest
Molecular glue degrader function of SPOP enhances STING-dependent immunotherapy efficacy in melanoma models. [Abstract]2025 Oct 28:e191772. PMID: 41148213
용액&용해도
DMSO : 4.55 mg/mL (15.81 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
순도&문서
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Data Sheet (269 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 3.4757 mL | 17.3786 mL | 34.7572 mL | 86.8931 mL |
| 5 mM | 0.6951 mL | 3.4757 mL | 6.9514 mL | 17.3786 mL | |
| 10 mM | 0.3476 mL | 1.7379 mL | 3.4757 mL | 8.6893 mL | |
| 15 mM | 0.2317 mL | 1.1586 mL | 2.3171 mL | 5.7929 mL |
Epiblastin A Related Classifications
HY-114858 Related Classifications
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