16470-02-3
16470-02-3
Chemical Structure
Epiblastin A
- CAS 番号: 16470-02-3
- Formula:C12H10ClN7
- Molecular Weight:287.71
IUPAC Name: 6-(3-chlorophenyl)pteridine-2,4,7-triamine
InChIKey: ZWNKKZSRANLVEW-UHFFFAOYSA-N
SMILES: NC1=NC(N)=C2N=C(C(N)=NC2=N1)C3=CC=CC(Cl)=C3
Biological Activity: Epiblastin A is an ATP competitive casein kinase 1 (CK1) inhibitor with IC50s of 8.9, 0.5, and 4.7 µM for CK1α, CK1δ, and CK1 ɛ, respectively. Epiblastin A induces reprogramming of epiblast stem cells into embryonic stem cells by inhibition of CK1[1].
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Epiblastin A | 99.44% | Epiblastin A is an ATP competitive casein kinase 1 (CK1) inhibitor with IC50s of 8.9, 0.5, and 4.7 µM for CK1α, CK1δ, and CK1 ɛ, respectively. Epiblastin A induces reprogramming of epiblast stem cells into embryonic stem cells by inhibition of CK1. | ||||||||||||||||||||
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References
Keywords
