1. PI3K/Akt/mTOR
  2. PI3K
  3. TG 100713

TG 100713 

Cat. No.: HY-13514 Purity: 98.63%
Handling Instructions

TG 100713 is an inhibitor of PI3K, with IC50s of 24, 50, 165, and 215 nM for PI3Kδ, γ, α and β isoforms respectively.

For research use only. We do not sell to patients.

TG 100713 Chemical Structure

TG 100713 Chemical Structure

CAS No. : 925705-73-3

Size Price Stock Quantity
5 mg USD 70 In-stock
Estimated Time of Arrival: December 31
10 mg USD 110 In-stock
Estimated Time of Arrival: December 31
50 mg USD 410 In-stock
Estimated Time of Arrival: December 31
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200 mg   Get quote  

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Customer Review

Based on 1 publication(s) in Google Scholar

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Description

TG 100713 is an inhibitor of PI3K, with IC50s of 24, 50, 165, and 215 nM for PI3Kδ, γ, α and β isoforms respectively[1].

IC50 & Target[1]

PI3Kδ

24 nM (IC50)

PI3Kγ

50 nM (IC50)

PI3Kα

165 nM (IC50)

PI3Kβ

215 nM (IC50)

In Vitro

TG100713 (10 μM; 48 or 72 h) strongly inhibits endothelial cell (EC) proliferation[1].

Molecular Weight

254.25

Formula

C₁₂H₁₀N₆O

CAS No.

925705-73-3

SMILES

OC1=CC=CC(C2=NC3=C(N)N=C(N)N=C3N=C2)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
  4°C 2 years
In solvent -80°C 6 months
  -20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 6.41 mg/mL (25.21 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 3.9331 mL 19.6657 mL 39.3314 mL
5 mM 0.7866 mL 3.9331 mL 7.8663 mL
10 mM 0.3933 mL 1.9666 mL 3.9331 mL
*Please refer to the solubility information to select the appropriate solvent.
References
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Keywords:

TG 100713TG100713TG-100713PI3KPhosphoinositide 3-kinasePI3KδPI3KγPI3KαPI3KβisoformInhibitorinhibitorinhibit

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Product Name:
TG 100713
Cat. No.:
HY-13514
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