Acetyl-CoA Carboxylase-IN-1
Based on 1 Customer Validation
Acetyl-CoA Carboxylase-IN-1 is a potent acetyl-CoA carboxylase (ACC) inhibitor with an IC50 value of ＜5 nM. Acetyl-CoA Carboxylase-IN-1 has antibacterial activity.
For research use only. We do not sell to patients.
- Purity: 99.18%
- CAS No.: 179343-23-8
- Formula: C13H9Br2N5
- Molecular Weight:395.05
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
Description
In Vitro
Acetyl-CoA Carboxylase-IN-1 (compound 1; 0.012-25 μM; E. coli) has antibacterial activity with MIC values of >25, 3.13, 25, 0.39, 1.56, 0.1 μM for WT, WT+ PMBN, ΔacrAB, ΔacrAB+PMBN, ΔtolC, and ΔtolC+ PMBN, respectively[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 179343-23-8
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Appearance Solid
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Molecular Weight 395.05
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Formula C13H9Br2N5
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Color Off-white to light yellow
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SMILES
BrC1=C(C2=CC3=CN=C(N=C3N=C2N)N)C(Br)=CC=C1
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
In Vitro:
DMSO : 33.33 mg/mL (84.37 mM; ultrasonic and warming and heat to 60°C; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (272 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.5313 mL | 12.6566 mL | 25.3133 mL | 63.2831 mL |
| 5 mM | 0.5063 mL | 2.5313 mL | 5.0627 mL | 12.6566 mL | |
| 10 mM | 0.2531 mL | 1.2657 mL | 2.5313 mL | 6.3283 mL | |
| 15 mM | 0.1688 mL | 0.8438 mL | 1.6876 mL | 4.2189 mL | |
| 20 mM | 0.1266 mL | 0.6328 mL | 1.2657 mL | 3.1642 mL | |
| 25 mM | 0.1013 mL | 0.5063 mL | 1.0125 mL | 2.5313 mL | |
| 30 mM | 0.0844 mL | 0.4219 mL | 0.8438 mL | 2.1094 mL | |
| 40 mM | 0.0633 mL | 0.3164 mL | 0.6328 mL | 1.5821 mL | |
| 50 mM | 0.0506 mL | 0.2531 mL | 0.5063 mL | 1.2657 mL | |
| 60 mM | 0.0422 mL | 0.2109 mL | 0.4219 mL | 1.0547 mL | |
| 80 mM | 0.0316 mL | 0.1582 mL | 0.3164 mL | 0.7910 mL |
Acetyl-CoA Carboxylase-IN-1 Related Classifications
HY-152117 Related Classifications
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