Catestatin sCst
Catestatin sCst is a negative control peptide with a scrambled amino acid sequence. Catestatin sCst fails to activate human mast cells and is used to verify the specificity of Catestatin action.
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- Formel: C104H164N32O27S
- Molecular Weight:2326.68
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biologische Aktivität
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Chemical Information
- Reinheit & Dokumentation
- Verweise
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Help & FAQs
Biologische Aktivität
Catestatin sCst (2500 nM-5 μM; 40 min) does not induce degranulation of LAD2 human mast cells or human peripheral blood-derived mast cells[1].
Catestatin sCst (10 μM; 30 min) does not induce release of LTC4, PGD2, or PGE2 from LAD2 human mast cells[1].
Catestatin sCst (10 μM; 6 hr) does not induce protein production of GM-CSF, MCP-1/CCL2, MIP-1α/CCL3, or MIP-1β/CCL4 in LAD2 human mast cells[1].
Catestatin sCst (0.32 μM; 3 hr) does not induce chemotaxis of LAD2 human mast cells[1].
Catestatin sCst (5 μM; 5 min) does not induce phosphorylation of ERK, JNK, or p38 MAPKs in LAD2 human mast cells[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Cell Line:LAD2 human mast cell line
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Concentration:10 μM
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Incubation Time:6 hr
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Result:Exerted no effect on protein production of GM-CSF, MCP-1/CCL2, MIP-1α/CCL3, or MIP-1β/CCL4 from LAD2 cells.
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Cell Line:LAD2 human mast cell line
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Concentration:5 μM
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Incubation Time:5 min
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Result:Exerted no effect on phosphorylation of ERK, JNK, or p38 MAPKs in LAD2 cells.
Chemical Information
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Molecular Weight 2326.68
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Formel C104H164N32O27S
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SMILES
O=C(N[C@@H](CCCCN)C(N[C@@H](CC(C)C)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CO)C(N[C@@H](CC1=CC=CC=C1)C(N[C@@H](CCCNC(N)=N)C(N[C@@H](C)C(N[C@@H](CC2=CC=C(C=C2)O)C(N[C@@H](C)C(N[C@@H](CCCNC(N)=N)C(NCC(N[C@@H](CC3=CC=CC=C3)C(N[C@@H](CCCNC(N)=N)C(NCC(N4[C@@H](CCC4)C(NCC(N5[C@@H](CCC5)C(N[C@@H](CCC(N)=O)C(N[C@@H](CC(C)C)C(O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)=O)[C@H](CCSC)N
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Sequence
Met-Lys-Leu-Ser-Ser-Ser-Phe-Arg-Ala-Tyr-Ala-Arg-Gly-Phe-Arg-Gly-Pro-Gly-Pro-Gln-Leu
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Sequence Shortening
MKLSSSFRAYARGFRGPGPQL
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
Catestatin sCst Related Classifications
HY-P3395A Related Classifications
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- Catestatin sCst
- PERK
- JNK
- p38 MAPK
- extracellular signal-regulated kinase
- human mast cells
- macrophage inflammatory protein-1a/CCL3
- macrophage inflammatory protein-1b/CCL4
- prostaglandin E2
- monocyte chemotactic protein-1/CCL2
- leukotriene C4
- granulocyte-macrophage colony-stimulating factor
- c-Jun N-terminal kinase
- prostaglandin D2
- Inhibitor
- inhibitor
- inhibit