DHODH-IN-20
DHODH-IN-20 (Compound 133) is a potent inhibitor of DHODH. DHODH is present in the inner membrane of human mitochondria and is an iron-containing flavin-dependent enzyme. DHODH-IN-20 inhibits tumor growth. DHODH-IN-20 has the potential for the research of acute myelogenous leukemia.
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- CAS. Nr.: 2639835-02-0
- Formel: C24H25F4N3O3
- Molecular Weight:479.47
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biologische Aktivität
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MOLM-13 | IC50 |
0.02 nM
Compound: 133
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Antiproliferative activity against human MOLM-13 cells assessed as reduction in cell viability measured for 72 hrs by cell titer glo assay
Antiproliferative activity against human MOLM-13 cells assessed as reduction in cell viability measured for 72 hrs by cell titer glo assay
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[PMID: 35178168] |
Chemical Information
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CAS. Nr. 2639835-02-0
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Molecular Weight 479.47
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Formel C24H25F4N3O3
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SMILES
O=C(NC1=CC=CC=C1C)C2=CC(F)=C(C3=CN(C)C(C(C)(O)C)=N3)C=C2O[C@@H](C)C(F)(F)F
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
DHODH-IN-20 Related Classifications
HY-144371 Related Classifications
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