Mafenide propionate
Mafenide propionate is a dual inhibitor of dihydropteroate synthase (Dihydropteroate synthase) and carbonic anhydrase (Carbonic anhydrase). Mafenide propionate disrupts nucleotide biosynthesis by inhibiting the de novo base synthesis pathway, thereby exerting broad-spectrum antibacterial and cytotoxic effects without inducing mutations. Mafenide propionate can be used for wound assessment and promotes the formation of healthy granulation tissue, making it suitable for scenarios such as mesh skin grafting. Mafenide propionate has been widely used in studies on diseases associated with burn wound infections, acute and chronic wounds, blast injuries, open fractures, and necrotizing fasciitis.
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- CAS. Nr.: 12001-72-8
- Formel: C10H16N2O4S
- Molecular Weight:260.31
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Speicherung:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biologische Aktivität
Chemical Information
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CAS. Nr. 12001-72-8
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Molecular Weight 260.31
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Formel C10H16N2O4S
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SMILES
O=C(CC)O.O=S(N)(C1=CC=C(CN)C=C1)=O
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Versand
Room temperature in continental US; may vary elsewhere.
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Speicherung
Please store the product under the recommended conditions in the Certificate of Analysis.
Reinheit & Dokumentation
Verweise
Calculators
Konzentration (Stammlösung) × Volumen (Stammlösung) = Konzentration (Ziellösung) × Volumen (Ziellösung)
- Mafenide propionate
- 12001-72-8
- Carbonic Anhydrase
- Bacterial
- Dihydrofolate reductase (DHFR)
- dihydrofolate synthase
- de novo bases synthesis pathway
- liver cells
- carbonic anhydrase
- bacterial biofilms
- fungal biofilms
- nucleotide biosynthesis
- necrotizing fasciitis
- burn wound infections
- severe burn injury
- Inhibitor
- inhibitor
- inhibit