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Art. -Nr.: HY-126233A

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PAT-347 sodium

PAT-347 sodium is an Autotaxin (ATX) inhibitor. ATX is a secretory enzyme that hydrolyzes lysophosphatidylcholine (LPC) and regulates lysophosphatidic acid (LPA) production in the blood.

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CAS. Nr.: 2650082-35-0
Formel: C₂₈H₂₀ClF₂N₂NaO₃S
Molecular Weight:560.97

Speicherung:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (271 KB)

PAT-347 sodium Chemical Structure

CAS. Nr.: 2650082-35-0

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Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biologische Aktivität
- Beschreibung
- IC₅₀ & Target
Chemical Information
Reinheit & Dokumentation
Verweise
Calculators
Help & FAQs
Classifications
Bioz

Biologische Aktivität

Beschreibung

PAT-347 sodium is an Autotaxin (ATX) inhibitor. ATX is a secretory enzyme that hydrolyzes lysophosphatidylcholine (LPC) and regulates lysophosphatidic acid (LPA) production in the blood^[1]^[2].

IC₅₀ & Target

Autotaxin (ATX)^[1]

Alle Phosphodiesterase (PDE) Isoform-spezifische Produkte anzeigen :

Chemical Information

CAS. Nr. 2650082-35-0
Molecular Weight 560.97
Formel C₂₈H₂₀ClF₂N₂NaO₃S
SMILES

O=C(C1=C(F)C(SC2=C(C)N(CC(N3C4=C(C5(CC5)C3)C=CC=C4)=O)C6=C2C=CC(Cl)=C6F)=CC=C1)O[Na]
Versand

Room temperature in continental US; may vary elsewhere.
Speicherung

Please store the product under the recommended conditions in the Certificate of Analysis.

Reinheit & Dokumentation

Select Batch:

Reinheit: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (271 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

Verweise

[1]. Chen Y, et al. Design, synthesis and anti-fibrosis evaluation of imidazo [1, 2–a] pyridine derivatives as potent ATX inhibitors[J]. Bioorganic & Medicinal Chemistry, 2021, 46: 116362.

[2]. Joncour A, et al. Discovery, structure–activity relationship, and binding mode of an imidazo [1, 2-a] pyridine series of autotaxin inhibitors[J]. Journal of Medicinal Chemistry, 2017, 60(17): 7371-7392.

Calculators

Molaritätsrechner

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Konzentration Konzentration

Volumen Volumen

Molecular Weight Molecular Weight

Verdünnungsrechner

Konzentration _{(Stammlösung)} × Volumen _{(Stammlösung)} = Konzentration _{(Ziellösung)} × Volumen _{(Ziellösung)}

Konzentration _{(Stammlösung)} Konzentration _{(Stammlösung)}

Volumen _{(Stammlösung)} Volumen _{(Stammlösung)}

Konzentration _{(Ziellösung)} Konzentration _{(Ziellösung)}

Volumen _{(Ziellösung)} Volumen _{(Ziellösung)}

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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MOQ

Minimum order quantity

100 mg

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Biologische Aktivität
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- IC₅₀ & Target
Chemical Information
Reinheit & Dokumentation
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PAT-347 sodium

Alle Phosphodiesterase (PDE) Isoform-spezifische Produkte anzeigen

Biologische Aktivität

Chemical Information

Reinheit & Dokumentation

Verweise

Calculators

Help & FAQs

PAT-347 sodium Related Classifications

HY-126233A Related Classifications