Metap2 - methionine aminopeptidase 2 Gene

Also Known as p67; Amp2; Mnpep; p67eIF2; 4930584B20Rik; A930035J23Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 56307

Summary

Predicted to enable Aminopeptidase activity and metalloexopeptidase activity. Predicted to be involved in N-terminal protein amino acid modification; peptidyl-methionine modification; and protein processing. Predicted to act upstream of or within proteolysis. Predicted to be located in cytosol and plasma membrane. Is expressed in brain and telencephalon. Orthologous to human METAP2 (methionyl Aminopeptidase 2). [provided by Alliance of Genome Resources, Apr 2022]

Metap2 Products (1)

mRNA Protein Name
NM_019648.3 NP_062622.1 methionine aminopeptidase 2

Gene Ontology

  • Molecular Function
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
15544353 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

methionine aminopeptidase 2

  • MAP 2

  • eIF-2-associated p67

  • initiation factor 2-associated 67 kDa glycoprotein

  • initiation factor 2-associated protein (p67)

  • metAP 2

  • peptidase M 2

Recombinant Metap2 Proteins

Cat. No. Product Name Accession Purity
HY-P75925 METAP2/Methionine aminopeptidase 2 Protein, Mouse (sf9, His) O08663 (A2-Y478) ≥ 85%, as determined by reducing SDS-PAGE.

Related Agents

  • Clinical Phase
  • Pre-clinical Phase

Clinical Phase

Bioactive Molecules (1)
Cat. No. Product Name Effect
Purity Phase
HY-14811 Beloranib Inhibitor 89.63% Phase 3

Pre-clinical Phase

Bioactive Molecules (12)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-128147 MetAP-2-IN-6 Inhibitor 99.55% Unkown
HY-120868 TP-004 Inhibitor 99.17% Unkown
HY-114196 Aclimostat Inhibitor 98.0% Unkown
HY-109188 Relzomostat Inhibitor / Unkown
HY-156959 Ovalicin Inhibitor / Unkown
HY-118953 LAF389 Inhibitor / Unkown
HY-119062 A-800141 Inhibitor / Unkown
HY-133806 Fumarranol Inhibitor / Unkown
HY-182419 A-849519 Inhibitor / Unkown
HY-182781 Anticancer agent 313 Inhibitor / Unkown
HY-122225 JNJ-4929821 Inhibitor / Unkown
HY-116861 A-357300 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Metap2 NCBI NCBI:10988