JAK-IN-38
JAK-IN-38 (Compound 1) is a JAK inhibitor, with IC50s of 0.03, 0.06, 0.12, 0.44 μM for Tyk2, JAK3, JAK2, JAK1 respectively. JAK-IN-38 is a collagen VII (C7) inducer and has anti-inflammatory activity. JAK-IN-38 can upregulate the expression of COL7A1 mRNA in donor-derived keratinocytes and works together with Gentamicin (HY-A0276A) to boost overall C7 levels.
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- Formule: C25H28N6O3
- Masse moléculaire:460.53
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Stockage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
Activité biologique
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Tyk2 0.03 μM (IC50) |
JAK3 0.06 μM (IC50) |
JAK2 0.12 μM (IC50) |
JAK1 0.44 μM (IC50) |
Chemical Information
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Masse moléculaire 460.53
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Formule C25H28N6O3
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SMILES
[H][C@@]1(C2CC3CC1C[C@@](C3)(C2)O)NC(C4=C(N=CC(C5=CC=C6C=CN(C6=C5)CC(N)=O)=N4)N)=O
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureté et documentation
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
JAK-IN-38 Related Classifications
HY-162862 Related Classifications
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