Endothelin-3, human, mouse, rabbit, rat TFA
Based on 1 publication(s) in Google Scholar
Endothelin-3, human, mouse, rabbit, rat TFA (Endothelin 3 (Rat,Human) TFA) is an adhesion stimulant. Endothelin-3, human, mouse, rabbit, rat TFA stimulates the adhesion of enteric neural crest cells to various ECM components. Endothelin-3, human, mouse, rabbit, rat TFA plays an important role in the maintenance and self-renewal of intestinal progenitor cells, participates in the migration of enteric neural crest cells, and helps maintain a suitable environment for the colonization of enteric neural crest cells. Endothelin-3, human, mouse, rabbit, rat TFA acts synergistically with the β1-integrin signaling pathway during enteric nervous system development. Endothelin-3, human, mouse, rabbit, rat TFA can be used in studies related to distal aganglionosis.
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- Pureté: 99.57%
- Formule: C123H169F3N26O35S4.xC2HF3O2
- Masse moléculaire:2757.07 (free base)
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Stockage:
Sealed storage, away from moisture.
Powder -80°C, 2 years , -20°C, 1 year* In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications Citing Use of MedChemExpress (MCE) Endothelin-3, human, mouse, rabbit, rat TFA
More
Activité biologique
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β1-integrin |
Endothelin-3, human, mouse, rabbit, rat (100 nM-1 μM) TFA significantly enhances the adhesion capacity of mouse E12.5 YFP-labeled enteric neural crest cells cultured on fibronectin, increases the number and size of focal adhesions, and promotes the formation of lamellipodia[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Cys-Thr-Cys-Phe-Thr-Tyr-Lys-Asp-Lys-Glu-Cys-Val-Tyr-Tyr-Cys-His-Leu-Asp-Ile-Ile-Trp(Disulfide bridge: Cys1-Cys15, Cys3-Cys11)
CTCFTYKDKECVYYCHLDIIW(Disulfide bridge: Cys1-Cys15, Cys3-Cys11)
Chemical Information
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Appearance Solid
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Masse moléculaire 2757.07 (free base)
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Formule C123H169F3N26O35S4.xC2HF3O2
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Color White to off-white
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Synonyms
Endothelin 3 (Rat,Human) TFA
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Sealed storage, away from moisture
Powder -80°C 2 years -20°C 1 year * In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)
Publications (1)
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Journal Impact Factor
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Most Recent
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Sci Adv
A human mucosal melanoma organoid platform for modeling tumor heterogeneity and exploring immunotherapy combination options. [Abstract]2023 Oct 27;9(43):eadg6686. PMID: 37889972
Solvant et solubilité
H2O : 50 mg/mL (Need ultrasonic)
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Working solution concentration: 0.22 mg/mL
This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.
Pureté et documentation
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Fiche technique (282 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Portuguese - PT (252 KB)
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Instruction de manipulation (2659 KB)
Références
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
- Endothelin-3, human, mouse, rabbit, rat
- Endothelin 3 (Rat,Human)
- Endothelin Receptor
- Integrin
- Endothelin receptor type B
- distal aganglionosis
- enteric nervous system
- ARP2/3-WAVE2 pathway
- enteric neural crest cell
- focal adhesions
- lamellipodia formation
- β1-integrin
- extracellular matrix components
- actin cytoskeleton remodelling
- Inhibitor
- inhibitor
- inhibit