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Cat. No.: HY-160548

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mTOR inhibitor-18

mTOR inhibitor-18 (Example 106) is a mTOR inhibitor. mTOR inhibitor-18 can be used for mTOR related research, such as cancer, immune disorders, cardiovascular disease, viral infection, inflammation, metabolism/endocrine function disorders and neurological disorders.

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CAS No.: 2170358-67-3
Formule: C₂₂H₂₁N₇OS
Masse moléculaire:431.51

Stockage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (268 KB)

mTOR inhibitor-18 Chemical Structure

CAS No.: 2170358-67-3

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Use of MCE Products

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Activité biologique
- Description
- In Vivo
Chemical Information
Pureté et documentation
Références
Calculators
Help & FAQs
Classifications
Bioz

Activité biologique

Description

Voir tous les produits spécifiques à Isoform mTOR :

In Vivo

Rat PK properties of mTOR inhibitor-18 (Example 106)^{[1]^{.

Dose (mg/kg)
C_max (μg/mL)
AUC_0-t (μg·h/mL)
t_1/2 (h)
CL (L/h/kg)
F%

IV (5 mg/kg)
21.2
41.455
1.416
0.122

PO (10 mg/kg)
9.987
73.44
3.258
0.247
89}}

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.

Chemical Information

CAS No. 2170358-67-3
Masse moléculaire 431.51
Formule C₂₂H₂₁N₇OS
SMILES

S=C(NC1=CC=C(C2=NN3C=CC=C3C(N4CCOCC4)=N2)C=C1)NC5=CC=CN=C5
Livraison

Room temperature in continental US; may vary elsewhere.
Stockage

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureté et documentation

Select Batch:

Pureté: 99.98%

Assay: 99.98%

ee.: 99.98%

Fiche technique (268 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instruction de manipulation (2659 KB)

Références

[1]. Chuangxin GUO, et al. Mechanistic target of rapamycin signaling pathway inhibitors and therapeutic applications. WO2017219800. thereof.

Calculators

Calculateur de molarité

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass Mass

Concentration Concentration

Volume Volume

Molecular Weight Molecular Weight

Calculateur de dilution

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

Concentration _(start) Concentration _(start)

Volume _(start) Volume _(start)

Concentration _(final) Concentration _(final)

Volume _(final) Volume _(final)

Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Bioz

Keywords

MOQ

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100 mg

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Activité biologique
- Description
- In Vivo
Chemical Information
Pureté et documentation
Références

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mTOR inhibitor-18

Voir tous les produits spécifiques à Isoform mTOR