L2H2-6OTD
L2H2-6OTD, containing one to four G-quadruplex binding loops, is a telomeric inhibitor analogue. l2H2-6OTD has telomerase inhibitory activity with an IC50 value of 15 nM.
For research use only. We do not sell to patients.
- CAS No.: 1016263-75-4
- Formula: C30H30N10O8
- Molecular Weight:658.62
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| HeLa | IC50 |
7.4 μM
Compound: fig. 9, R1C3-1
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Cytotoxicity against human HeLa cells
Cytotoxicity against human HeLa cells
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10.1039/C0MD00241K |
| KB 3-1 | IC50 |
>10 μM
Compound: 6c
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Cytotoxicity against wild type human KB3-1 cells after 4 days by MTT assay
Cytotoxicity against wild type human KB3-1 cells after 4 days by MTT assay
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[PMID: 20409709] |
| KB-V1 | IC50 |
>10 μM
Compound: 6c
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Cytotoxicity against multidrug-resistant human KBV1 cells expressing MDR1 after 4 days by MTT assay
Cytotoxicity against multidrug-resistant human KBV1 cells expressing MDR1 after 4 days by MTT assay
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[PMID: 20409709] |
Chemical Information
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CAS No. 1016263-75-4
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Molecular Weight 658.62
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Formula C30H30N10O8
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SMILES
NCCCC[C@H](NC(C1=COC(C2=COC3=N2)=N1)=O)C4=NC(C5=NC(C6=NC(C(N[C@H](C7=NC3=CO7)CCCCN)=O)=CO6)=CO5)=CO4
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
L2H2-6OTD Related Classifications
HY-148200 Related Classifications
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