PDE7-IN-4
Based on 1 Customer Validation
PDE7-IN-4 is a phosphodiesterase 7 (PDE7) inhibitor with activity that increases intracellular cyclic adenosine monophosphate (cAMP) levels. PDE7-IN-4 shows potential inhibitory effects in neurotransmission and anti-inflammatory applications. PDE7-IN-4 exerts its biological activity by acting on the cAMP/cAMP response element binding protein (CREB) pathway. The development of PDE7-IN-4 aims to improve its pharmacokinetic characteristics to more effectively target neurodegenerative diseases and other inflammation-related diseases.
For research use only. We do not sell to patients.
- Purity: 98.55%
- CAS No.: 18741-24-7
- Formula: C14H10N2OS
- Molecular Weight:254.31
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Storage:Powder -20°C, 3 years , 4°C, 2 years ; In solvent -80°C, 6 months , -20°C, 1 month
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Biological Activity
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Chemical Information
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Solvent & Solubility
- Purity & Documentation
- References
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Help & FAQs
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Biological Activity
Chemical Information
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CAS No. 18741-24-7
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Appearance Solid
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Molecular Weight 254.31
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Formula C14H10N2OS
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Color White to off-white
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SMILES
S=C(N1)N(C2=CC=CC=C2)C(C3=C1C=CC=C3)=O
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Powder -20°C 3 years 4°C 2 years In solvent -80°C 6 months -20°C 1 month
Solvent & Solubility
DMSO : 50 mg/mL (196.61 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Purity & Documentation
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Data Sheet (273 KB)
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SDS (393 KB)
- English - EN (393 KB)
- Français - FR (393 KB)
- Deutsch - DE (393 KB)
- Norwegian - NO (393 KB)
- Español - ES (393 KB)
- Swedish - SV (393 KB)
- Italian - IT (393 KB)
- Korean - KR (393 KB)
- Portuguese - PT (393 KB)
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Handling Instructions (2659 KB)
References
Complete Stock Solution Preparation Table
Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
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| DMSO | 1 mM | 3.9322 mL | 19.6610 mL | 39.3221 mL | 98.3052 mL |
| 5 mM | 0.7864 mL | 3.9322 mL | 7.8644 mL | 19.6610 mL | |
| 10 mM | 0.3932 mL | 1.9661 mL | 3.9322 mL | 9.8305 mL | |
| 15 mM | 0.2621 mL | 1.3107 mL | 2.6215 mL | 6.5537 mL | |
| 20 mM | 0.1966 mL | 0.9831 mL | 1.9661 mL | 4.9153 mL | |
| 25 mM | 0.1573 mL | 0.7864 mL | 1.5729 mL | 3.9322 mL | |
| 30 mM | 0.1311 mL | 0.6554 mL | 1.3107 mL | 3.2768 mL | |
| 40 mM | 0.0983 mL | 0.4915 mL | 0.9831 mL | 2.4576 mL | |
| 50 mM | 0.0786 mL | 0.3932 mL | 0.7864 mL | 1.9661 mL | |
| 60 mM | 0.0655 mL | 0.3277 mL | 0.6554 mL | 1.6384 mL | |
| 80 mM | 0.0492 mL | 0.2458 mL | 0.4915 mL | 1.2288 mL | |
| 100 mM | 0.0393 mL | 0.1966 mL | 0.3932 mL | 0.9831 mL |
PDE7-IN-4 Related Classifications
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