1. Immunology/Inflammation
  2. STING

diABZI STING agonist-1 Tautomerism 

Cat. No.: HY-112921
Handling Instructions

diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs.

For research use only. We do not sell to patients.

diABZI STING agonist-1 Tautomerism Chemical Structure

diABZI STING agonist-1 Tautomerism Chemical Structure

CAS No. : 2138498-18-5

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Customer Review

Other Forms of diABZI STING agonist-1 Tautomerism:

  • Biological Activity

  • Technical Information

  • Purity & Documentation

  • References

Description

diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs.

IC50 & Target

EC50: 130 nM (human STNG in PBMCs) [1].

In Vitro

diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with an EC50s of 130 for human PBMCs.

In Vivo

diABZI STING agonist-1 (Tautomerism) is a selective stimulator of interferon genes (STING) receptor agonist, with EC50s of 130, 186 nM for human and mouse, respectively. At a concentration of 1 μM, diABZI STING agonist-1 (compound 3) demonstrates high selectivity against more than 350 kinases tested[1].

Solvent & Solubility
In Vitro: 

10 mM in DMSO

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.1766 mL 5.8828 mL 11.7655 mL
5 mM 0.2353 mL 1.1766 mL 2.3531 mL
10 mM 0.1177 mL 0.5883 mL 1.1766 mL
*Please refer to the solubility information to select the appropriate solvent.
References
Molecular Weight

849.94

Formula

C₄₂H₅₁N₁₃O₇

CAS No.

2138498-18-5

SMILES

O=C(N)C1=CC(N/C(N2C/C=C/CN3/C(NC4=C3C(OCCCN5CCOCC5)=CC(C(N)=O)=C4)=N/C(C6=CC(C)=NN6CC)=O)=N\C(C7=CC(C)=NN7CC)=O)=C2C(OC)=C1

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Shipping

Room temperature in continental US; may vary elsewhere

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Product Name:
diABZI STING agonist-1 Tautomerism
Cat. No.:
HY-112921
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diABZI STING agonist-1 Tautomerism

Cat. No.: HY-112921