1. Immunology/Inflammation
  2. STING
  3. STING agonist-20

STING agonist-20 (compound 95) is a potent STING agonist used in the synthesis of XMT-2056. STING agonist-20 can be used as a vaccine adjuvant in the study of cancer and other inflammatory, immune diseases.

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STING agonist-20 Chemical Structure

STING agonist-20 Chemical Structure

CAS No. : 2591300-72-8

Size Price Stock Quantity
1 mg USD 330 In-stock
5 mg USD 990 In-stock
10 mg USD 1540 In-stock
25 mg USD 3080 In-stock
50 mg USD 4800 In-stock
100 mg   Get quote  
200 mg   Get quote  

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Based on 1 publication(s) in Google Scholar

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Description

STING agonist-20 (compound 95) is a potent STING agonist used in the synthesis of XMT-2056. STING agonist-20 can be used as a vaccine adjuvant in the study of cancer and other inflammatory, immune diseases[1].

Molecular Weight

753.76

Formula

C36H39N11O8

CAS No.
Appearance

Solid

Color

White to light yellow

SMILES

O=C(C1=C(N=C(O1)C)CC)NC2=NC3=CC(C(N)=O)=CN=C3N2C/C=C/CN4C5=C(OCCCO)C=C(C(N)=O)C=C5N=C4NC(C6=C(N=C(O6)C)CC)=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage
Powder -20°C 3 years
4°C 2 years
In solvent -80°C 6 months
-20°C 1 month
Solvent & Solubility
In Vitro: 

DMSO : 80 mg/mL (106.13 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.3267 mL 6.6334 mL 13.2668 mL
5 mM 0.2653 mL 1.3267 mL 2.6534 mL
View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

  • Molarity Calculator

  • Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Mass
=
Concentration
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Volume
×
Molecular Weight *

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)

This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start)

C1

×
Volume (start)

V1

=
Concentration (final)

C2

×
Volume (final)

V2

In Vivo Dissolution Calculator
Please enter the basic information of animal experiments:

Dosage

mg/kg

Animal weight
(per animal)

g

Dosing volume
(per animal)

μL

Number of animals

Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Calculation results:
Working solution concentration: mg/mL
Purity & Documentation

Purity: 99.75%

References

Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month. When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

Optional Solvent Concentration Solvent Mass 1 mg 5 mg 10 mg 25 mg
DMSO 1 mM 1.3267 mL 6.6334 mL 13.2668 mL 33.1671 mL
5 mM 0.2653 mL 1.3267 mL 2.6534 mL 6.6334 mL
10 mM 0.1327 mL 0.6633 mL 1.3267 mL 3.3167 mL
15 mM 0.0884 mL 0.4422 mL 0.8845 mL 2.2111 mL
20 mM 0.0663 mL 0.3317 mL 0.6633 mL 1.6584 mL
25 mM 0.0531 mL 0.2653 mL 0.5307 mL 1.3267 mL
30 mM 0.0442 mL 0.2211 mL 0.4422 mL 1.1056 mL
40 mM 0.0332 mL 0.1658 mL 0.3317 mL 0.8292 mL
50 mM 0.0265 mL 0.1327 mL 0.2653 mL 0.6633 mL
60 mM 0.0221 mL 0.1106 mL 0.2211 mL 0.5528 mL
80 mM 0.0166 mL 0.0829 mL 0.1658 mL 0.4146 mL
100 mM 0.0133 mL 0.0663 mL 0.1327 mL 0.3317 mL
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STING agonist-20 Related Classifications

Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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Product Name:
STING agonist-20
Cat. No.:
HY-148068
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