Lck-IN-6
Lck-IN-6 (Compound 12g) is a Lck inhibitor with an IC50 of 3 nM. Lck-IN-6 inhibits the production of IL-2. Lck-IN-6 can be used in the research of rheumatoid arthritis and inflammatory bowel disease.
For research use only. We do not sell to patients.
- CAS No.: 918870-43-6
- Formula: C24H26N6O3
- Molecular Weight:446.51
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Biological Activity
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Chemical Information
- Purity & Documentation
- References
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Help & FAQs
Biological Activity
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Lck 3 nM (IC50) |
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| Jurkat | IC50 |
0.054 μM
Compound: 12g
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Inhibition of IL2 production in Jurkat E6-1 T cells by ELISA
Inhibition of IL2 production in Jurkat E6-1 T cells by ELISA
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[PMID: 16997556] |
Lck-IN-6 inhibits recombinant human active Lck with an IC50 of 3 nM[1].
Lck-IN-6 inhibits IL-2 production in stimulated Jurkat E6-1 human acute T cell leukemia cells with an IC50 of 0.054 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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CAS No. 918870-43-6
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Molecular Weight 446.51
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Formula C24H26N6O3
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SMILES
OC1=CC=C(C(=C1)NC2=NC(=NC(OCCN3CCOCC3)=C2)N4C=NC=5C=CC=CC54)C
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Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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