1. Protein Tyrosine Kinase/RTK
    JAK/STAT Signaling
  2. EGFR
  3. EMI56

EMI56 

Cat. No.: HY-131067
Handling Instructions

EMI56, the derivative of EMI1, displays greater potency toward mutant EGFR than EMI1. EMI56 inhibits EGFR triple mutants.

For research use only. We do not sell to patients.

EMI56 Chemical Structure

EMI56 Chemical Structure

CAS No. : 2414374-41-5

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Description

EMI56, the derivative of EMI1, displays greater potency toward mutant EGFR than EMI1. EMI56 inhibits EGFR triple mutants[1].

IC50 & Target[1]

EGFRL858R/T790M/C797S

 

EGFRdel19 T790M C797S

 

In Vitro

EMI56 inhibits EGFR ex19del/T790M/C797S and EGFR L858R/T790M/C797S. EMI56 can be used in the research of mutant EGFR-associated, drug-resistant non-small-cell lung cancer (NSCLC)[1].

Molecular Weight

348.40

Formula

C₂₁H₂₀N₂O₃

CAS No.

2414374-41-5

SMILES

CCN(CC)C1=C(C)C=C2C(OC(C(C3=NC(C=CC=C4)=C4O3)=C2)=O)=C1

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

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Keywords:

EMI56EMI 56EMI-56EGFREpidermal growth factor receptorErbB-1HER1derivativeex19delT790MC797SL858RNSCLCInhibitorinhibitorinhibit

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