M4K2308
M4K2308 is a selective ether-linked inhibitor of ALK2 with an IC50 of 2 nM. M4K2308 exhibits exceptional selectivity for ALK2 over ALK5 (IC50 of 224 nM). M4K2308 has the potential for the study of diffuse intrinsic pontine glioma (DIPG) research.
For research use only. We do not sell to patients.
- CAS No.: 3034840-18-8
- Formula: C26H29N3O4
- Molecular Weight:447.53
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Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
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ALK2 2 nM (IC50) |
ALK5 224 nM (IC50) |
Chemical Information
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CAS No. 3034840-18-8
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Molecular Weight 447.53
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Formula C26H29N3O4
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SMILES
COC(C=C1C2=C3C(C4=CC=C(N5CCNCC5)C=C4OCC3)=CN=C2)=C(C(OC)=C1)OC
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Shipping
Room temperature in continental US; may vary elsewhere.
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Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)