2-Ethyl-3-methylpyrazine
Based on 1 Customer Validation
2-Ethyl-3-methylpyrazine is a GABAA receptor potentiator, Antibacterial agent and Antifungal agent, with a Kp of 1.14 mM for GABAA. 2-Ethyl-3-methylpyrazine forms via the Maillard reaction in sunflower seeds and also exists in the crust of wheat bread. 2-Ethyl-3-methylpyrazine regulates mood or states of consciousness via central GABAA receptors. 2-Ethyl-3-methylpyrazine inhibits the growth of Ralstonia solanacearum and Magnaporthe oryzae. 2-Ethyl-3-methylpyrazine acts as an anxiolytic. 2-Ethyl-3-methylpyrazine is one of the sources of cocoa aroma, imparting nutty, corn-like, burnt, cereal, roasted and earthy flavors to foods. 2-Ethyl-3-methylpyrazine can be used in studies related to anxiety disorders and plant bacterial, fungal and oomycete infections.
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- CAS No.: 15707-23-0
- Formule: C7H10N2
- Masse moléculaire:122.17
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Stockage:
Store at room temperature 3 years.
In solvent -80°C, 2 years , -20°C, 1 year
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Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Activité biologique
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Chemical Information
- Pureté et documentation
- Références
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Help & FAQs
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HY-34439
2,5-Dimethylpyrazine
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HY-W067358
2-Methylpyrazine
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HY-W040790
2,6-Dimethylpyrazine
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HY-W040948
2-Ethylpyrazine
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HY-W015914
2,3-Dimethylpyrazine
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HY-14768
Favipiravir
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HY-34439R
2,5-Dimethylpyrazine (Standard)
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HY-W067358R
2-Methylpyrazine (Standard)
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HY-W040790R
2,6-Dimethylpyrazine (Standard)
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HY-W040948R
2-Ethylpyrazine (Standard)
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HY-N0264
Ligustrazine
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HY-B0271
Pyrazinamide
Activité biologique
2-Ethyl-3-methylpyrazine (0.01% (v/v), 0.8 mM) potently potentiates GABA-induced responses of bovine GABAₐ receptors expressed in Xenopus oocytes, with a maximum potentiation magnitude of 555% and a dissociation constant (Kp) of 1.14 mM[1].
2-Ethyl-3-methylpyrazine (335-672 µg/mL) inhibits the growth of Ralstonia solanacearum in a dose-dependent manner, with an inhibition rate of up to 95.9% at the concentration of 672 µg/mL[2].
2-Ethyl-3-methylpyrazine (168 µg/mL) completely inhibits the mycelial growth of Magnaporthe oryzae[2].
2-Ethyl-3-methylpyrazine inhibits the growth of the phytopathogenic fungus Gibberella moniliformis[2].
2-Ethyl-3-methylpyrazine inhibits the growth of the phytopathogenic fungus Phaeomoniella chlamydospora[2].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
2-Ethyl-3-methylpyrazine (100 mg/kg; i.p.; twice daily; 2 days) exhibits anti-anxiety activity in Mus musculus, as shown by significant increases in open arm entries and open arm stay time in an elevated plus maze test following 100 mg/kg intraperitoneal dosing twice daily for 2 days[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:ICR mice (male, 7-10 weeks old, 32-40 g)[1]
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Dosage:25 mg/kg; 100 mg/kg
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Administration:i.p.; single dose
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Result:Prolonged pentobarbital-induced sleeping time significantly relative to control at 100 mg/kg.
Doubled the sleeping time compared to control at 25 mg/kg.
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Animal Model:ICR mice (male, 7-10 weeks old, 32-40 g)[1]
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Dosage:100 mg/kg
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Administration:i.p.; twice daily; 2 days
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Result:Increased the number of entries into the open arms significantly relative to control.
Increased the duration of stay in the open arms significantly relative to control.
Chemical Information
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CAS No. 15707-23-0
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Appearance Liquid
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Masse moléculaire 122.17
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Formule C7H10N2
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SMILES
CCC1=C(N=CC=N1)C
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Structure Classification
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Initial Source
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Livraison
Room temperature in continental US; may vary elsewhere.
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Stockage
Store at room temperature 3 years
In solvent -80°C 2 years -20°C 1 year
Pureté et documentation
Références
[1]. Mitou M, et al. Effect of dried bonito (katsuobushi) and some of its components on GABAA receptors. Food Chem. 2008 Jun 1;108(3):840-6. [Content Brief]
[3]. Fayek NM, et al. A multifunctional study of naturally occurring pyrazines in biological systems; formation mechanisms, metabolism, food applications and functional properties. Crit Rev Food Sci Nutr. 2023;63(21):5322-5338. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
2-Ethyl-3-methylpyrazine Related Classifications
HY-W012832 Related Classifications
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