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  4. Gadopentetic acid

Gadopentetic acid  (Synonyms: Gd-DTPA; gadolinium complex)

Cat. No.: HY-107353 Purity: ≥99.0%
COA Handling Instructions

Gadopentetic acid (Gd-DTPA) is a paramagnetic contrast agent. Gadopentetic acid commonly implemented by a bolus intravenous injection in Dynamic contrast-enhanced MRI (DCE-MRI) studies. Gadopentetic acid also can be used for the research of nephrogenic systemic fibrosis (NSF).

For research use only. We do not sell to patients.

Gadopentetic acid Chemical Structure

Gadopentetic acid Chemical Structure

CAS No. : 80529-93-7

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Solution
10 mM * 1 mL in Water USD 55 In-stock
Estimated Time of Arrival: December 31
Solid + Solvent
10 mM * 1 mL
ready for reconstitution
 USD 55 In-stock
Estimated Time of Arrival: December 31
Solid
100 mg USD 50 In-stock
Estimated Time of Arrival: December 31
200 mg   Get quote  
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Based on 2 publication(s) in Google Scholar

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Description

Gadopentetic acid (Gd-DTPA) is a paramagnetic contrast agent. Gadopentetic acid commonly implemented by a bolus intravenous injection in Dynamic contrast-enhanced MRI (DCE-MRI) studies. Gadopentetic acid also can be used for the research of nephrogenic systemic fibrosis (NSF)[1][2].

In Vivo

Gadopentetic acid (Gd-DTPA) (tail vein injection; 2 and 5mmol/kg; single) shows systematic metabolic responses involving changes in lipid metabolism, glucose metabolism, TCA cycle, amino acid metabolism and gut microbiota functions in rats[1].

MCE has not independently confirmed the accuracy of these methods. They are for reference only.

Animal Model: rats[1]
Dosage: 2 and 5mmol/kg
Administration: tail vein injection, single
Result: Observed urinary and serum metabonomic recovery but the metabolic effects of high-dosed (5mmol/kg) lasted long.
Observed hyperlipidemia after Gd-DTPA injection.
Molecular Weight

547.57

Appearance

Solid

Formula

C14H20GdN3O10
CAS No.
SMILES

O=C1[O-][Gd+3]23([O-]4)([O-]5)([O-]6)([O-]7)[N](CC[N]2(CC5=O)CC4=O)(CC[N]3(CC7=O)CC6=O)C1.[H+].[H+]
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

4°C, sealed storage, away from moisture and light

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture and light)
Solvent & Solubility
In Vitro: 

H2O : 100 mg/mL (182.63 mM; Need ultrasonic)

DMSO : 1 mg/mL (1.83 mM; Need ultrasonic)

Preparing
Stock Solutions
Concentration Solvent Mass 1 mg 5 mg 10 mg
1 mM 1.8263 mL 9.1313 mL 18.2625 mL
5 mM 0.3653 mL 1.8263 mL 3.6525 mL
10 mM 0.1826 mL 0.9131 mL 1.8263 mL
*Please refer to the solubility information to select the appropriate solvent.
In Vivo:
  • 1.

    Add each solvent one by one:  PBS

    Solubility: 100 mg/mL (182.63 mM); Clear solution; Need ultrasonic

*All of the co-solvents are available by MCE.
Purity & Documentation
References
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Help & FAQs
  • Do most proteins show cross-species activity?

    Species cross-reactivity must be investigated individually for each product. Many human cytokines will produce a nice response in mouse cell lines, and many mouse proteins will show activity on human cells. Other proteins may have a lower specific activity when used in the opposite species.

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  • Dilution Calculator

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The dilution calculator equation

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This equation is commonly abbreviated as: C1V1 = C2V2

Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
× = ×
C1   V1   C2   V2

Keywords:

Gadopentetic acid80529-93-7Gd-DTPA gadolinium complexBiochemical Assay Reagentsparamagnetic contrastDynamic contrast-enhanced MRI (DCE-MRI)intravenous injectionnephrogenic systemic fibrosis (NSF)Inhibitorinhibitorinhibit

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