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Referencia número: HY-117569

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KF24345 free base

KF24345 free base is an orally active adenosine uptake inhibitor. KF24345 free base inhibits adenosine uptake by human, mouse, rabbit and hamster erythrocytes with IC₅₀ values of 59.5, 130.1, 104.2 and 30.9 nM, respectively. KF24345 free base has anti-inflammatory activity and can inhibit LPS-induced TNF-α production and leukopenia in mice.

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No. CAS: 178750-21-5
Fòrmula: C₃₁H₃₈N₆O₅
Peso molecular:574.67

Almacenamiento:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (270 KB)

KF24345 free base Chemical Structure

No. CAS: 178750-21-5

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

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Descripciòn

Ver todos los productos específicos de isoformas TNF Receptor :

Chemical Information

No. CAS 178750-21-5
Peso molecular 574.67
Fòrmula C₃₁H₃₈N₆O₅
SMILES

O=C(N(C1=C(C2=O)C=C(C=C1)C)C)N2C3CCN(CC3)C4=C5C=C(C(OCC)=CC5=NC(N6CCOCC6)=N4)OCC
Envío

Room temperature in continental US; may vary elsewhere.
Almacenamiento

Please store the product under the recommended conditions in the Certificate of Analysis.

Pureza y Documentación

Select Batch:

Pureza: 99.98%

Assay: 99.98%

ee.: 99.98%

Ficha de datos (270 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Instrucciones de manejo (2659 KB)

Referencias

[1]. Noji T, et al. KF24345, an adenosine uptake inhibitor, suppresses lipopolysaccharide-induced tumor necrosis factor-α production and leukopenia via endogenous adenosine in mice[J]. Journal of Pharmacology and Experimental Therapeutics, 2002, 300(1): 200-205. [Content Brief]

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

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KF24345 free base

Ver todos los productos específicos de isoformas TNF Receptor

Actividad biológica

Chemical Information

Pureza y Documentación

Referencias

Calculators

Help & FAQs

KF24345 free base Related Classifications

HY-117569 Related Classifications