L-796449
L-796449 is a potent PPARγ agonist. L-796449 shows neuroprotective. L-796449 has the potential for the research of stroke.
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- No. CAS: 194608-80-5
- Fòrmula: C28H27ClO4S
- Peso molecular:495.03
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
PPARγ[1]
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
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Animal Model:250 g adult male Fischer rats[1]
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Dosage:1 mg/kg (MCAO 10 minutes before IP injection)
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Administration:I.p.
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Result:Decreased MCAO-induced infarct size determined 2 and 7 days after the ischemic injury, inhibited MCAO-induced expression of iNOS and MMP-9 but did not affect COX-2 levels at the time examined; increased the expression of heme oxygenase-1 (HO-1) and inhibited NF-κB signaling.
Chemical Information
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No. CAS 194608-80-5
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Peso molecular 495.03
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Fòrmula C28H27ClO4S
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SMILES
O=C(CC1=CC=C(C(Cl)=C1)SCCCOC2=C(C3=C(C(C4=CC=CC=C4)=CO3)C=C2)CCC)O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
L-796449 Related Classifications
HY-123654 Related Classifications
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