Phospholipase D, peanut
Based on 1 Customer Validation
Phospholipase D, peanut is a phospholipase D (EC 3.1.4.4) of the PLD superfamily found in peanuts, acting as a phosphodiesterase and signaling enzyme with activity toward phosphatidylcholine. Phospholipase D hydrolyzes phosphatidylcholine to phosphatidic acid and choline, and catalyzes transphosphatidylation reactions. Phospholipase D can be used for the research of myocardial disease, ischemic heart disease, congestive heart failure, diabetic cardiomyopathy, cardiac hypertrophy, vascular abnormalities, breast cancer, gastric cancer, renal cancer, colorectal cancer.
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- No. CAS: 9001-87-0
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
- Pureza y Documentación
- Referencias
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Help & FAQs
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Actividad biológica
Phospholipase D hydrolyzes choline phospholipids to quantify propargylcholine incorporation[3].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
3.1.4.4
≥60 U/mg soild
One unit is defined as the amount of enzyme that catalyze the release of 1 μmol of choline from L-αphosphatidylcholineyolk) per hour at pH 5.6 and 30°C
Chemical Information
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No. CAS 9001-87-0
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Appearance Solid
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Color White to off-white
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SMILES
[Phospholipase D, peanut]
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
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Ficha de datos (265 KB)
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SDS (251 KB)
- English - EN (251 KB)
- Français - FR (251 KB)
- Deutsch - DE (251 KB)
- Norwegian - NO (251 KB)
- Español - ES (251 KB)
- Swedish - SV (251 KB)
- Italian - IT (251 KB)
- Korean - KR (251 KB)
- Portuguese - PT (251 KB)
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Instrucciones de manejo (2659 KB)
Referencias
[1]. Shukla SD, Halenda SP. Phospholipase D in cell signalling and its relationship to phospholipase C. Life sciences. 1991;48(9):851-66. [Content Brief]
[2]. Selvy PE, et al. Phospholipase D: enzymology, functionality, and chemical modulation. Chem Rev. 2011 Oct 12;111(10):6064-119. [Content Brief]
[3]. Jao CY, Roth M, Welti R, et al.. Metabolic labeling and direct imaging of choline phospholipids in vivo. Proceedings of the National Academy of Sciences of the United States of America. 2009 Sep 08;106(36):15332-7. [Content Brief]
[4]. Tappia PS, et al. Oxidative stress and redox regulation of phospholipase D in myocardial disease. Free Radic Biol Med. 2006 Aug 1;41(3):349-61. [Content Brief]
[5]. Foster DA, Xu L. Phospholipase D in cell proliferation and cancer. Mol Cancer Res. 2003 Sep;1(11):789-800. [Content Brief]
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
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