(R)-Amrubicin
(R)-Amrubicin ((R)-SM-5887) is an anthracycline that effectively treats lung cancer by intercalating into DNA and inhibiting topoisomerase II activity, which consequently hampers DNA replication as well as RNA and protein synthesis, leading to cell growth inhibition and apoptosis. This compound exhibits superior anti-tumor efficacy compared to traditional anthracycline drugs while lacking the cumulative cardiac toxicity typically associated with this drug class.
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- No. CAS: 92395-36-3
- Fòrmula: C25H25NO9
- Peso molecular:483.47
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Chemical Information
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Actividad biológica
Chemical Information
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No. CAS 92395-36-3
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Peso molecular 483.47
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Fòrmula C25H25NO9
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SMILES
CC([C@@](C1)(N)C[C@H](O[C@H]2OC[C@@H](O)[C@@H](O)C2)C(C1=C3O)=C(O)C4=C3C(C5=CC=CC=C5C4=O)=O)=O
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Synonyms
(R)-SM-5887
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
(R)-Amrubicin Related Classifications
HY-B0067B Related Classifications
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