(S)-ErSO
Based on 1 Customer Validation
(S)-ErSO is the dextrorotatory enantiomer of ErSO. (S)-ErSO is inactive in MCF-7 cells (from patent WO2020009958A1, compound (s)-105).
Para uso exclusivo en investigación. No vendemos a pacientes.
- Pureza: 99.40%
- No. CAS: 2407860-34-6
- Fòrmula: C22H13F6NO3
- Peso molecular:453.33
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
To place orders, for customer services and technical support, please contact: MedChemExpress USA
Tel: 609-228-6898 E-mail: [email protected] [email protected]
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Actividad biológica
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Chemical Information
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Solvente y solubilidad
- Pureza y Documentación
- Referencias
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Help & FAQs
Actividad biológica
(-)-ErSO induces dose-dependent death of MCF-7 cells. (+)-l05 is inactive[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 2407860-34-6
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Appearance Solid
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Peso molecular 453.33
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Fòrmula C22H13F6NO3
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Color White to light yellow
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SMILES
O=C1NC2=C(C=CC=C2C(F)(F)F)[C@]1(C3=CC=C(O)C=C3)C4=CC=C(OC(F)(F)F)C=C4
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Solvente y solubilidad
DMSO : 190 mg/mL (419.12 mM; Need ultrasonic; Hygroscopic DMSO has a significant impact on the solubility of product, please use newly opened DMSO)
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
Select the appropriate dissolution method based on your experimental animal and administration route.
- For the following dissolution methods, please ensure to first prepare a clear stock solution using an In Vitro approach and then sequentially add co-solvents:
- To ensure reliable experimental results, the clarified stock solution can be appropriately stored based on storage conditions. As for the working solution for In Vivo experiments, it is recommended to prepare freshly and use it on the same day.
- The percentages shown for the solvents indicate their volumetric ratio in the final prepared solution. If precipitation or phase separation occurs during preparation, heat and/or sonication can be used to aid dissolution.
Add each solvent one by one: 10% DMSO 90% (20% SBE-β-CD in Saline)
Solubility: ≥ 4.75 mg/mL (10.48 mM); Clear solution
This protocol yields a clear solution of ≥ 4.75 mg/mL (saturation unknown).
Taking 1 mL working solution as an example, add 100 μL DMSO stock solution (47.5 mg/mL) to 900 μL 20% SBE-β-CD in Saline, and mix evenly.
Preparation of 20% SBE-β-CD in Saline (4°C, storage for one week): 2 g SBE-β-CD powder is dissolved in 10 mL Saline, completely dissolve until clear.
Please enter the basic information of animal experiments:
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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.
Please enter your animal formula composition:
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%DMSO +
Recommended: Keep the proportion of DMSO in working solution below 2% if your animal is weak.
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%+
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+%Tween-80 + +
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%Saline +
The co-solvents required include: DMSO, . All of co-solvents are available by MedChemExpress (MCE). , Tween 80. All of co-solvents are available by MedChemExpress (MCE).
Working solution concentration: 0.22 mg/mL
Method for preparing stock solution: mg drug dissolved in μL DMSO. Stock solution concentration: mg/mL.
1. Take μL DMSO stock solution;
2. Add μL .
μL , mix evenly;
3. Then add μL Tween 80, mix evenly;
4. Then add μL
Please ensure that the stock solution in the first step is dissolved to a clear state, and add co-solvents in sequence. You can use ultrasonic heating (ultrasonic cleaner, recommended frequency 20-40 kHz), vortexing, etc. to assist dissolution.
Pureza y Documentación
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Ficha de datos (275 KB)
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SDS (252 KB)
- English - EN (252 KB)
- Français - FR (252 KB)
- Deutsch - DE (252 KB)
- Norwegian - NO (252 KB)
- Español - ES (252 KB)
- Swedish - SV (252 KB)
- Italian - IT (252 KB)
- Korean - KR (252 KB)
- Portuguese - PT (252 KB)
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Instrucciones de manejo (2659 KB)
Referencias
Complete Stock Solution Preparation Table
| Optional Solvent | Concentration Solvent Mass | 1 mg | 5 mg | 10 mg | 25 mg |
|---|---|---|---|---|---|
| DMSO | 1 mM | 2.2059 mL | 11.0295 mL | 22.0590 mL | 55.1475 mL |
| 5 mM | 0.4412 mL | 2.2059 mL | 4.4118 mL | 11.0295 mL | |
| 10 mM | 0.2206 mL | 1.1029 mL | 2.2059 mL | 5.5147 mL | |
| 15 mM | 0.1471 mL | 0.7353 mL | 1.4706 mL | 3.6765 mL | |
| 20 mM | 0.1103 mL | 0.5515 mL | 1.1029 mL | 2.7574 mL | |
| 25 mM | 0.0882 mL | 0.4412 mL | 0.8824 mL | 2.2059 mL | |
| 30 mM | 0.0735 mL | 0.3676 mL | 0.7353 mL | 1.8382 mL | |
| 40 mM | 0.0551 mL | 0.2757 mL | 0.5515 mL | 1.3787 mL | |
| 50 mM | 0.0441 mL | 0.2206 mL | 0.4412 mL | 1.1029 mL | |
| 60 mM | 0.0368 mL | 0.1838 mL | 0.3676 mL | 0.9191 mL | |
| 80 mM | 0.0276 mL | 0.1379 mL | 0.2757 mL | 0.6893 mL | |
| 100 mM | 0.0221 mL | 0.1103 mL | 0.2206 mL | 0.5515 mL |
(S)-ErSO Related Classifications
HY-132247B Related Classifications
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