SMK-17
SMK-17 is a selective, non-ATP-competitive MEK1/MEK2 inhibitor with IC50s of 62 nM and 56 nM, respectively. SMK-17 binds to the allosteric pocket of MEK1/2. SMK-17 induces apoptosis in tumor cell lines harboring β-catenin mutations.
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- No. CAS: 765958-29-0
- Fòrmula: C20H24ClF2IN4O2S
- Peso molecular:584.85
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
Chemical Information
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No. CAS 765958-29-0
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Peso molecular 584.85
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Fòrmula C20H24ClF2IN4O2S
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SMILES
O=S(NC1=CC=C(C(F)=C1NC2=CC=C(C=C2Cl)I)F)(N3CCC(CC3)NC(C)C)=O
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
SMK-17 Related Classifications
HY-12447 Related Classifications
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