U 88204
U 88204 is a potent HIV-1 reverse transcriptase (RT) inhibitor with an IC50 of 0.25 μM. U 88204 blocks HIV-1 replication in infected cells. U 88204 can be used for the research on HIV-infection and of acquired immunodeficiency syndrome (AIDs).
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- No. CAS: 136816-76-7
- Fòrmula: C21H25N5O
- Peso molecular:363.47
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Cell Line
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Type | Value | Description | References |
|---|---|---|---|---|
| MT2 | CC50 |
10 μM
Compound: 4
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Cytotoxic concentration against MT-2 cells
Cytotoxic concentration against MT-2 cells
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[PMID: 7684450] |
U 88204 (compound 11) potently blocks HIV-1 replication in MT-2/IIIb, PBMC/D34, and H9/IIIb cells with ED50 values of 0.3 μM, 0.001 μM, and 0.04 μM, respectively, while showing low cytotoxicity (CC50 > 10 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 136816-76-7
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Peso molecular 363.47
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Fòrmula C21H25N5O
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SMILES
O=C(C1=CC=2C=CC=CC2N1)N3CCN(C4=NC=CC=C4NC(C)C)CC3
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
U 88204 Related Classifications
HY-180417 Related Classifications
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