YM-254891
YM-254891 is a YM-254890 (HY-111557) analogue and Gαq/11 inhibitor. YM-254891 can be isolated from the fermentation broth of Chromobacterium sp. QS3666. YM-254891 inhibits ADP-induced platelet aggregation.
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- No. CAS: 726188-99-4
- Fòrmula: C47H71N7O15
- Peso molecular:974.10
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Almacenamiento:
Please store the product under the recommended conditions in the Certificate of Analysis.
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Actividad biológica
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Chemical Information
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Actividad biológica
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Microbial Metabolite |
YM-254891 inhibits 2MeSADP-induced Ca2+ influx in P2Y1-C6-15 cells with an IC50 of 0.23 μM[1].
YM-254891 inhibits ADP-induced platelet aggregation in platelet-rich plasma with an IC50 of 0.27 μM[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
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No. CAS 726188-99-4
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Peso molecular 974.10
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Fòrmula C47H71N7O15
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SMILES
CCC(N[C@@H]([C@H](O)C(C)C)C(O[C@@H]([C@@]1([H])C(N([C@@](C(O[C@@H]([C@@H](C(O[C@@H](C(N(C(C(N[C@H](C(N([C@H](C(N1)=O)C)C)=O)C)=O)=C)C)=O)CC2=CC=CC=C2)=O)NC(C)=O)C)=O)([H])[C@@H](C)OC)C)=O)C(C)C)=O)=O
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Structure Classification
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Initial Source
Chromobacterium sp
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Envío
Room temperature in continental US; may vary elsewhere.
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Almacenamiento
Please store the product under the recommended conditions in the Certificate of Analysis.
Pureza y Documentación
Referencias
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)
YM-254891 Related Classifications
HY-N17826 Related Classifications
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