Cers6 - ceramide synthase 6 Gene

Also Known as T1L; Lass6; 4732462C07Rik

Species: Mus musculus

Gene Type: protein coding
Gene ID: 241447

Summary

Enables sphingosine N-acyltransferase activity. Acts upstream of or within ceramide biosynthetic process. Located in endoplasmic reticulum. Is expressed in blastocyst; early embryo; genitourinary system; and limb mesenchyme. Orthologous to human CERS6 (ceramide synthase 6). [provided by Alliance of Genome Resources, Apr 2022]

Cers6 Products (2)

mRNA Protein Name
NM_001347161.2 NP_001334090.1 ceramide synthase 6 isoform 1
NM_172856.5 NP_766444.1 ceramide synthase 6 isoform 2

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables protein binding IPI
IPI: Inferred from physical interaction
26620563 MGI
enables sphingosine N-acyltransferase activity IDA
IDA: Inferred from direct assay
15823095 MGI
enables sphingosine N-acyltransferase activity IMP
IMP: Inferred from mutant phenotype
23760501 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within ceramide biosynthetic process IDA
IDA: Inferred from direct assay
15823095 MGI
involved in ceramide biosynthetic process IDA
IDA: Inferred from direct assay
26620563 MGI
involved in ceramide biosynthetic process IMP
IMP: Inferred from mutant phenotype
23760501 MGI
acts upstream of or within sphingolipid biosynthetic process IDA
IDA: Inferred from direct assay
15823095 MGI
Cellular Component GO Annotation Evidence References Source
located in endoplasmic reticulum IDA
IDA: Inferred from direct assay
15823095 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ceramide synthase 6

  • LAG1 homolog, ceramide synthase 6

  • LAG1 longevity assurance homolog 6

  • longevity assurance homolog 6

  • sphingoid base N-palmitoyltransferase CERS6

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (8)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-19542 C6 Ceramide Inducer 99.82% Unkown
HY-RS29482 CERS6 Cattle Pre-designed siRNA Set A / Unkown
HY-133488 ST1072 Inhibitor / Unkown
HY-146905S CER6-2’S-d9 99.0% Unkown
HY-RS02541 CERS6 Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-119633 Perfluidone / Unkown
HY-146899S CER6-2’R-d9 99.0% Unkown
HY-W766368 C6 Ceramide-13C2,d2 / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Cers6 NCBI NCBI:253782