Prrt1 - proline-rich transmembrane protein 1 Gene

Also Known as G5b; NG5; Bat4; Bat-4; DSPD1; ORF31; SynDIG4; D17H6S54E

Species: Mus musculus

Gene Type: protein coding
Gene ID: 260297

Summary

Enables signaling receptor regulator activity. Involved in several processes, including long-term synaptic depression; protein localization to cell surface; and regulation of AMPA Receptor activity. Acts upstream of or within several processes, including learning or memory; long-term synaptic potentiation; and synapse organization. Located in postsynaptic density membrane and synaptic vesicle membrane. Orthologous to human PRRT1 (proline rich transmembrane protein 1). [provided by Alliance of Genome Resources, Apr 2022]

Prrt1 Products (4)

mRNA Protein Name
NM_001368728.1 NP_001355657.1 proline-rich transmembrane protein 1 isoform 2
NM_001368729.1 NP_001355658.1 proline-rich transmembrane protein 1 isoform 3
NM_001368730.1 NP_001355659.1 proline-rich transmembrane protein 1 isoform 4
NM_030890.2 NP_112152.1 proline-rich transmembrane protein 1 isoform 1

Gene Ontology

  • Molecular Function
  • Biological Process
  • Cellular Component
Molecular Function GO Annotation Evidence References Source
enables signaling receptor regulator activity IDA
IDA: Inferred from direct assay
29490264 MGI
Biological Process GO Annotation Evidence References Source
acts upstream of or within learning or memory IMP
IMP: Inferred from mutant phenotype
29490264 MGI
involved in long-term synaptic depression IMP
IMP: Inferred from mutant phenotype
31216424 MGI
acts upstream of or within long-term synaptic potentiation IMP
IMP: Inferred from mutant phenotype
29490264 MGI
acts upstream of or within protein localization IMP
IMP: Inferred from mutant phenotype
29490264 MGI
involved in protein localization to cell surface IMP
IMP: Inferred from mutant phenotype
31216424 MGI
involved in protein phosphorylation IMP
IMP: Inferred from mutant phenotype
31216424 MGI
involved in regulation of AMPA receptor activity IDA
IDA: Inferred from direct assay
29490264 MGI
involved in regulation of AMPA receptor activity IMP
IMP: Inferred from mutant phenotype
31216424 MGI
acts upstream of or within synapse organization IMP
IMP: Inferred from mutant phenotype
29490264 MGI
Cellular Component GO Annotation Evidence References Source
is active in glutamatergic synapse IDA
IDA: Inferred from direct assay
36429079 MGI
is active in postsynaptic density membrane IDA
IDA: Inferred from direct assay
36429079 MGI
located in postsynaptic density membrane IDA
IDA: Inferred from direct assay
29490264 MGI
located in synaptic vesicle membrane IDA
IDA: Inferred from direct assay
29490264 MGI
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

proline-rich transmembrane protein 1

  • dispanin subfamily D member 1

  • synapse differentiation-induced protein 4

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (3)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-106244 DOTATATE 99.94% Yes
HY-106244A DOTATATE acetate 99.95% Unkown
HY-RS11241 PRRT1 Human Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Prrt1 NCBI NCBI:80863