Usp7 - ubiquitin specific peptidase 7 Gene

Also Known as Hausp

Species: Rattus norvegicus

Gene Type: protein coding
Gene ID: 360471

Summary

Enables identical protein binding activity and thiol-dependent Deubiquitinase. Involved in positive regulation of apoptotic process; protein deubiquitination; and regulation of protein stability. Predicted to be located in XY body and cytoplasm. Predicted to be part of protein-containing complex. Predicted to be active in cytosol and nucleus. Orthologous to human USP7 (ubiquitin specific peptidase 7). [provided by Alliance of Genome Resources, Apr 2022]

Usp7 Products (1)

mRNA Protein Name
NM_001024790.2 NP_001019961.2 ubiquitin carboxyl-terminal hydrolase 7

Gene Ontology

  • Molecular Function
  • Biological Process
Molecular Function GO Annotation Evidence References Source
enables cysteine-type deubiquitinase activity IDA
IDA: Inferred from direct assay
16328052 RGD
enables identical protein binding IPI
IPI: Inferred from physical interaction
16111684 RGD
Biological Process GO Annotation Evidence References Source
involved in positive regulation of apoptotic process IDA
IDA: Inferred from direct assay
16328052 RGD
involved in protein deubiquitination IDA
IDA: Inferred from direct assay
16328052 RGD
involved in regulation of protein stability IDA
IDA: Inferred from direct assay
16111684 RGD
EXP: Inferred from Experiment IDA: Inferred from direct assay IPI: Inferred from physical interaction IMP: Inferred from mutant phenotype IGI: Inferred from genetic interaction IEP: Inferred from expression pattern
Protein Preferred Names Protein Names

ubiquitin carboxyl-terminal hydrolase 7

  • deubiquitinating enzyme 7

  • herpes-virus-associated ubiquitin-specific protease

  • herpesvirus-associated ubiquitin-specific protease

  • rHAUSP

  • ubiquitin specific peptidase 7 (herpes virus-associated)

  • ubiquitin specific protease 7 (herpes virus-associated)

Related Agents

  • Pre-clinical Phase

Pre-clinical Phase

Bioactive Molecules (23)
Cat. No. Product Name
Effect
Purity
Rare Diseases
HY-13453 BAY 11-7082 Inhibitor 99.98% Unkown
HY-158039 YCH2823 Inhibitor 99.87% Unkown
HY-101666 HBX 41108 Inhibitor 98.91% Unkown
HY-136910 USP7-797 Inhibitor 99.09% Unkown
HY-148369 U7D-1 Inhibitor 99.68% Unkown
HY-175360 USP7 Ligand-Linker Conjugates 1 Inhibitor 99.92% Unkown
HY-183282 LC-U7-44 Inhibitor / Unkown
HY-162794 YCH3124 Inhibitor / Unkown
HY-175359 USP7-IN-19 Inhibitor / Unkown
HY-180826 USP7 ligand-2 Ligand / Unkown
HY-153942 USP7-IN-12 Inhibitor / Unkown
HY-183689 OAT-4828 Inhibitor / Unkown
HY-159175 XM-U-14 Degrader / Unkown
HY-175358 PROTAC USP7 Degrader-1 Degrader / Unkown
HY-175793 USP7 ligand-1 Ligand / Unkown
HY-183078 P6620 Inhibitor / Unkown
HY-159964 USP7-IN-16 Inhibitor / Unkown
HY-49319 USP7-IN-14 Inhibitor / Unkown
HY-180793 PROTAC USP7 Degrader-2 Degrader / Unkown
HY-168121 USP7-IN-15 Inhibitor / Unkown
HY-124739 HBX 28258 Inhibitor / Unkown
HY-164544 USP7-055 Inhibitor / Unkown
HY-183942 USP7-IN-20 Inhibitor / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Usp7 NCBI NCBI:7874