HBX 28258
HBX 28258 is a selective USP7 inhibitor, with an IC50 of 22.6 μM. HBX 28258 can covalently binds to Cys223 located in the catalytic core of USP7, inhibits its deubiquitinating activity, promotes MDM2 protein degradation, and activates p53.
For research use only. We do not sell to patients.
- CAS No.: 1426544-54-8
- Formula: C26H30ClN3O
- Molecular Weight:435.99
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
|
USP7 22.6 μM (IC50) |
Chemical Information
-
CAS No. 1426544-54-8
-
Molecular Weight 435.99
-
Formula C26H30ClN3O
-
SMILES
O=C(C1=CC2=C(N=C3C(CCCC3)=C2Cl)C=C1)NCCCN(CC)CC4=CC=CC=C4
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)