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Cat. No.: HY-175359

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USP7-IN-19

USP7-IN-19 is a USP7 inhibitor. USP7-IN-19 can be used for synthesis of PROTAC USP7 Degrader-1 (HY-175358).

For research use only. We do not sell to patients.

Formula: C₃₀H₃₅N₅O₄
Molecular Weight:529.63

Storage:

Please store the product under the recommended conditions in the Certificate of Analysis.

Data Sheet (266 KB)

USP7-IN-19 Chemical Structure

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Top Publications Citing

Use of MCE Products

Fluorescent Dye

Strong Fluorescence Signal / Multi-Disciplinary Applications / High Fluorescence Specificity

Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References
Calculators
Help & FAQs
Classifications
Bioz

Biological Activity

Description

USP7-IN-19 is a USP7 inhibitor. USP7-IN-19 can be used for synthesis of PROTAC USP7 Degrader-1 (HY-175358)^[1].

IC₅₀ & Target^[1]

USP7

All Deubiquitinase Isoforms :

Chemical Information

Molecular Weight 529.63
Formula C₃₀H₃₅N₅O₄
SMILES

O=C1C2=NN(C)C(C3=CC=C(OCC)C=C3)=C2N=CN1CC4(O)CCN(C(C[C@@H](C)C5=CC=CC=C5)=O)CC4
Shipping

Room temperature in continental US; may vary elsewhere.
Storage

Please store the product under the recommended conditions in the Certificate of Analysis.

Purity & Documentation

Select Batch:

Purity: 99.98%

Assay: 99.98%

ee.: 99.98%

Data Sheet (266 KB)
COA (2659 KB)
Elemental Analysis Report (2659 KB)
HNMR (2659 KB)
CNMR (2659 KB)
RP-HPLC (2659 KB)
NP-HPLC (2659 KB)
MS (2659 KB)
LCMS (2659 KB)
IR (2659 KB)
GC (2659 KB)
OR (2659 KB)
SDS-PAGE (2659 KB)
SEC-HPLC (2659 KB)
Other Report (2659 KB)
Handling Instructions (2659 KB)

References

[1]. Wittenburg S, et al. Enhancing Solubility in VHL-Based PROTACs: Optimized USP7 Degraders for Improved Developability. J Med Chem. 2025 Jul 17. [Content Brief]

Calculators

Molarity Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

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Dilution Calculator

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Help & FAQs

How should lyophilized recombinant proteins be reconstituted and stored?

1. Before opening the cap, centrifuge the vial at 13000 rpm for 20-30 seconds. This step will ensure that any lyophilized powder that may have adhered to the cap or walls is collected at the bottom of the vial, minimizing the risk of product loss.

Keywords

100 mg

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Biological Activity
- Description
- IC₅₀ & Target
Chemical Information
Purity & Documentation
References

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USP7-IN-19

All Deubiquitinase Isoforms

Biological Activity

Chemical Information

Purity & Documentation

References

Calculators

Help & FAQs

USP7-IN-19 Related Classifications

HY-175359 Related Classifications