2. Gene
  3. Rab27a - RAB27A, member RAS oncogene family Gene

Rab27a - RAB27A, member RAS oncogene family Gene

  • Gene
  • Protein
  • Agent
  • Ortholog
Rattus norvegicus

Also known as ram

Gene ID: 50645 | Gene type: protein coding

About Rab27a

Summary

Enables protein domain specific binding activity. Predicted to be involved in several processes, including complement-dependent cytotoxicity; regulation of vesicle-mediated transport; and secretion by cell. Predicted to act upstream of or within several processes, including leukocyte degranulation; melanocyte differentiation; and pigment granule localization. Located in Weibel-Palade body; apical plasma membrane; and secretory granule membrane. Human ortholog(s) of this gene implicated in Griscelli syndrome type 2 and non-Langerhans-cell histiocytosis. Orthologous to human RAB27A (RAB27A, member Ras oncogene family). [provided by Alliance of Genome Resources, Apr 2022]

Rab27a Products(1)

mRNA Protein Name
NM_017317.2 NP_059013.1 ras-related protein Rab-27A
Protein Preferred Names Protein Names

ras-related protein Rab-27A

GTP-binding protein Ram

low Mr GTP-binding protein

rab-27

ram p25

Related Agents

Pre-clinical Phase
Bioactive Molecules (4)
Cat. No. Product Name Effect
Purity Rare Diseases
HY-125792 Nexinhib20 Inhibitor 99.86% Unkown
HY-137677B GTPγS tetralithium Activator 96.04% Unkown
HY-RS11537 RAB27A Human Pre-designed siRNA Set A Pre-designed Set / Unkown
HY-RS16309 Rab27a Mouse Pre-designed siRNA Set A Pre-designed Set / Unkown

Orthologs Information

Species Symbol Source ID
Homo sapiens Rab27a NCBI NCBI:5873