GTPγS tetralithium

Cat. No.: HY-137677B Purity: 81.60%: FAQs
Data Sheet SDS COA Handling Instructions

Molarity Calculator

GTPγS (tetralithium) is a G-protein activator that protects proteins from proteolytic degradation, stimulates GLUT4 translocation in a tyrosine kinase-dependent manner, stimulate phospholipases and induce actin polymerization. GTPγS (tetralithium) to couple with G- protein α, to study its effect on kinase activity. GTPγS (tetralithium) acts as a component of lysis buffer.

For research use only. We do not sell to patients.

GTPγS tetralithium Chemical Structure

CAS No. : 94825-44-2

Size	Price	Stock	Quantity
1 mg	USD 240	In-stock	Estimated Time of Arrival: December 31
5 mg		Get quote
10 mg		Get quote

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Biological Activity
Purity & Documentation
References
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Description

Molecular Weight

562.98

Formula

C₁₀H₁₂Li₄N₅O₁₃P₃S

CAS No.

94825-44-2

Appearance

Solid

Color

White to off-white

SMILES

O[C@H]1[C@@H](O)[C@H](N2C(NC(N)=NC3=O)=C3N=C2)O[C@@H]1COP(OP(OP(S[Li])(O[Li])=O)(O[Li])=O)(O[Li])=O

Shipping

Room temperature in continental US; may vary elsewhere.

Storage

-20°C, sealed storage, away from moisture

*In solvent : -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture)

Solvent & Solubility

In Vitro:

H₂O : ≥ 100 mg/mL (177.63 mM)

*"≥" means soluble, but saturation unknown.

Preparing
Stock Solutions

Concentration Solvent Mass	1 mg	5 mg	10 mg

1 mM	1.7763 mL	8.8813 mL	17.7626 mL
5 mM	0.3553 mL	1.7763 mL	3.5525 mL
10 mM	0.1776 mL	0.8881 mL	1.7763 mL

View the Complete Stock Solution Preparation Table

* Please refer to the solubility information to select the appropriate solvent. Once prepared, please aliquot and store the solution to prevent product inactivation from repeated freeze-thaw cycles.
Storage method and period of stock solution: -80°C, 6 months; -20°C, 1 month (sealed storage, away from moisture). When stored at -80°C, please use it within 6 months. When stored at -20°C, please use it within 1 month.

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.

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Dilution Calculator

Mass (g) = Concentration (mol/L) × Volume (L) × Molecular Weight (g/mol)

Concentration _(start) × Volume _(start) = Concentration _(final) × Volume _(final)

This equation is commonly abbreviated as: C₁V₁ = C₂V₂

In Vivo Dissolution Calculator

Please enter the basic information of animal experiments:

Dosage

mg/kg

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μL

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Recommended: Prepare an additional quantity of animals to account for potential losses during experiments.

Calculation results:

Working solution concentration: mg/mL

This product has good water solubility, please refer to the measured solubility data in water/PBS/Saline for details.

The concentration of the stock solution you require exceeds the measured solubility. The following solution is for reference only.If necessary, please contact MedChemExpress (MCE).

Purity & Documentation

Purity: ≥94.0%

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Data Sheet (273 KB) SDS (393 KB)

COA (250 KB)

Handling Instructions (2659 KB)

References

[1]. Julie G Hensler, et al. Differential Regulation of 5-HT1A Receptor-G Protein Interactions in Brain Following Chronic Antidepressant Administration. Neuropsychopharmacology. 2002 May;26(5):565-73. [Content Brief]

[2]. Li-Bin Liu, et al. Insulin recruits GLUT4 from distinct compartments via distinct traffic pathways with differential microtubule dependence in rat adipocytes. J Biol Chem. 2003 Aug 8;278(32):30157-69. doi: 10.1074/jbc.M301511200. [Content Brief]

[3]. Xufeng Wu, et al. Rab27a is an essential component of melanosome receptor for myosin Va. Mol Biol Cell. 2002 May;13(5):1735-49. [Content Brief]

[4]. Pilar Sánchez-Blázquez, et al. Brain-specific Galphaz interacts with Src tyrosine kinase to regulate Mu-opioid receptor-NMDAR signaling pathway. Cell Signal. 2009 Sep;21(9):1444-54. [Content Brief]

Complete Stock Solution Preparation Table

Optional Solvent	Concentration Solvent Mass	1 mg	5 mg	10 mg	25 mg

H₂O	1 mM	1.7763 mL	8.8813 mL	17.7626 mL	44.4066 mL
	5 mM	0.3553 mL	1.7763 mL	3.5525 mL	8.8813 mL
	10 mM	0.1776 mL	0.8881 mL	1.7763 mL	4.4407 mL
	15 mM	0.1184 mL	0.5921 mL	1.1842 mL	2.9604 mL
	20 mM	0.0888 mL	0.4441 mL	0.8881 mL	2.2203 mL
	25 mM	0.0711 mL	0.3553 mL	0.7105 mL	1.7763 mL
	30 mM	0.0592 mL	0.2960 mL	0.5921 mL	1.4802 mL
	40 mM	0.0444 mL	0.2220 mL	0.4441 mL	1.1102 mL
	50 mM	0.0355 mL	0.1776 mL	0.3553 mL	0.8881 mL
	60 mM	0.0296 mL	0.1480 mL	0.2960 mL	0.7401 mL
	80 mM	0.0222 mL	0.1110 mL	0.2220 mL	0.5551 mL
	100 mM	0.0178 mL	0.0888 mL	0.1776 mL	0.4441 mL

* Note: If you choose water as the stock solution, please dilute it to the working solution, then filter and sterilize it with a 0.22 μm filter before use.