GTP-γ-S

GTPγS (30-100 μM; 1-3 h) maintains Rab27a in a GTP-bound state that supports its indirect association with melanocyte myosin Va (MC MV) and MC MVΔD in B16 F10 melanocyte lysates, whereas GDP reduces this association^[1].
GTPγS (1 mM; 20 min) stimulates glucose transport in electrically permeabilized rat primary adipocytes via a microtubule-independent mechanism^[2].
GTPγS (1 mM; 20 min) induces GLUT4 translocation to the plasma membrane in electrically permeabilized rat primary adipocytes with more residual cytoplasmic GLUT4 signals than insulin^[2].
GTPγS (1 mM; 20 min) does not disrupt the association of tubulin with GLUT4-containing membranes in electrically permeabilized rat primary adipocytes, in contrast to insulin^[2].
GTPγS (10 μM) defines nonspecific [³⁵S]GTPγS binding in coronal sections of rat brain (including dorsal raphe nucleus, median raphe nucleus, and forebrain areas)^[3].
GTPγS (10 μM; 15 min) formed Gαi2GTPγS that enhances recombinant human Src tyrosine kinase activity with an ED₅₀ of 20 nM, while formed GαzGTPγS reduces this stimulatory effect^[4].

MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.