83 Results for "

glycosidase

" in MedChemExpress (MCE) Product Catalog:
Products (83)

83 Results for "glycosidase" in MCE Product Catalog:

9
9 Publications Verification
Cat. No.: HY-13005
CAS No.: 53185-12-9
Purity:  98.97%
Synonyms: D-Fagomine
Fagomine is a mild glycosidase inhibitor. The Ki of the iminosugar Fagomine is 4.8 μM, 39 μM, and 70 μM for Amyloglucosidase (A.niger), β-Glucosidase (bovine), and Isomaltase (yeast), respectively.
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2
2 Cited Publications
Cat. No.: HY-P2929
CAS No.: 83534-39-8
Research Areas:  

Cancer

PNGase F, a glycosidase, catalyzes the cleavage of an internal glycoside bond in an oligosaccharide. PNGase F removes nearly all N-linked oligosaccharides from glycoproteins. PNGase F can release N-glycans from glycoproteins in glycoanalytical workflows .
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2
2 Cited Publications
Cat. No.: HY-P2929A
CAS No.: 83534-39-8
Target:  

Glycosidase

Research Areas:  

Cancer

PNGase F-Fast is a glycosidase that catalyzes the cleavage of internal glycosidic bonds in oligosaccharides. PNGase F-Fast removes almost all N-linked oligosaccharides from glycoproteins. PNGase F-Fast can release N-glycans from glycoproteins in the sugar analysis workflow. The cleavage site is: the glycosidic bond between the innermost N-acetylglucosamine and asparagine. PNGase F-Fast is an improved reagent that allows for rapid deglycosylation of antibodies and antibody fusions within minutes .
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2
2 Cited Publications
Cat. No.: HY-P2929C
CAS No.: 83534-39-8
Research Areas:  

Cancer

PNGase F (Lyophilized), a glycosidase, catalyzes the cleavage of an internal glycoside bond in an oligosaccharide. PNGase F (Lyophilized) removes nearly all N-linked oligosaccharides from glycoproteins. PNGase F (Lyophilized) can release N-glycans from glycoproteins in glycoanalytical workflows .
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1
1 Cited Publications
Cat. No.: HY-15927
CAS No.: 2492-87-7
4-Nitrophenyl β-D-glucopyranoside is a chromogenic substrate for β-glucosidase. 4-Nitrophenyl β-D-glucopyranoside is converted to a colored product, p-nitrophenol that is easily detected spectrophotometrically at 405 nm when used in a β-glycosidase assay. 4-Nitrophenyl β-D-glucopyranoside is hydrolysed through intramolecular nucleophilic catalysis by the phosphate group in the 2-position. 4-Nitrophenyl β-D-glucopyranoside is promising for research of postmenopausal osteoporosis .
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1
1 Cited Publications
Cat. No.: HY-B2221
CAS No.: 9004-34-6
Synonyms: Pectin glycosidase
Cellulose (Pectin glycosidase) is a natural high molecular weight polysaccharide found in many plants and organisms. It is widely used in manufacturing industries, such as in paper making, textiles, food and medicine, etc. As a renewable resource, Cellulose is biodegradable and sustainable, and can also be used to manufacture chemicals such as Cellulose Esters, Cellulose Acetate and Cellulose Nitrate. In addition, Cellulose is often used as a food additive to increase the stability and quality of food.
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1
1 Cited Publications
Cat. No.: HY-KE7057

O-Glycosidase is highly specific and can release Galβ1-3GalNAc from serine, threonine residues or as part of a glycopeptide or glycoprotein. Applied to glycoprotein biosynthesis analysis, O-glycan bioactive protein O-glycosylation detection and binding site analysis.

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Cat. No.: HY-137822
CAS No.: 10357-27-4
Purity:  99.68%
Synonyms: 4-Nitrophenyl a-D-mannopyranoside
p-Nitrophenyl α-D-mannopyranoside (4-Nitrophenyl α-D-mannopyranoside) is a chromogenic glycosidic ligand. p-Nitrophenyl α-D-mannopyranoside features a sugar moiety (α-D-mannopyranose) with the mannose-characteristic axial hydroxyl group at the C2 position and a ligand portion (p-nitrophenol) that provides ultraviolet-visible light absorption properties. p-Nitrophenyl α-D-mannopyranoside can be used to determine glycosidase activity and characterize the sugar recognition properties of lectins (such as Concanavalin A (HY-P2149)) .
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Cat. No.: HY-147084
Purity:  98.20%
Target:  

ADC Linkers

Research Areas:  

Metabolic Disease Cancer

KY371 is a click chemistry reagent containing an alkyne group. KY371 is a broad-range glycosidase inhibitor. KY371 can combine with proteomic analysis of targeted protein to study glycosidases .
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Cat. No.: HY-P2955
CAS No.: 149371-12-0
Target:  

Glycosidase

Research Areas:  

Cancer

Heparinase II is a glycosidase targeting heparin and heparan sulfate. Heparinase II is promising for research of glycosaminoglycan structure-function analysis, anticoagulant agents and tumor microenvironment modulation .
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Cat. No.: HY-137490
CAS No.: 77471-44-4
Purity:  99.93%
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

4-Methylumbelliferyl α-L-arabinofuranoside is the glycosidase substrate .
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Cat. No.: HY-121811
CAS No.: 484-33-3
Purity:  99.81%
Synonyms: Lanceolatin C
Pongamol (Lanceolatin C) is an orally active flavonoid with an IC50 of 75 μM and a Ki of 58 μM against PTPase-1B, and an IC50 of 103.5 μM against intestinal α-Glycosidase. Pongamol reduces the release of IL‑1β, TNF‑α, COX‑2 and iNOS in cells, reverses the nuclear translocation of NF‑κB, and upregulates the levels of Beclin 1 and LC3 Ⅱ/LC3 Ⅰ. Pongamol promotes glucose uptake by increasing the level of GLUT4 on the surface of skeletal muscle cells. Pongamol inhibits epithelial-mesenchymal transition by suppressing the FAK/Akt-mTOR signaling pathway. Pongamol inhibits neuronal cytotoxicity, suppresses cell apoptosis and extends the lifespan of Caenorhabditis elegans by activating the MAPKs/Nrf2 signaling pathway. Pongamol exerts hypoglycemic effects in diabetic mouse models. Pongamol exhibits antibacterial activity. Pongamol alleviates oxidative stress, neuroinflammation, deposition and excessive phosphorylation of Tau Protein, and restores autophagy function in Alzheimer's disease mouse models by inhibiting the Akt/mTOR signaling pathway. Pongamol is applicable to research related to Alzheimer's disease, type 2 diabetes, non-small cell lung cancer and postprandial hyperglycemia .
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Cat. No.: HY-E70042
CAS No.: 9025-44-9
Target:  

Endogenous Metabolite

Research Areas:  

Metabolic Disease

Nucleoside hydrolase (IAGNH) is a glycosidase. Nucleoside hydrolase (IAGNH) catalyzes the cleavage of the N-glycosidic bond in nucleosides to enable the recycling of the nucleobases and Rib .
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Cat. No.: HY-18598
CAS No.: 1579991-61-9
Target:  

Insecticide

Research Areas:  

Infection

Chitinase-IN-1 is an insecticide that can inhibit the activity of chitinase and N-acetylglucosaminidase. The inhibition percentages for glycosidase and N-acetylglucosaminidase at concentrations of 50 uM and 20 uM are 75% and 67%, respectively.
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Cat. No.: HY-N7529
CAS No.: 54795-58-3
Research Areas:  

Others

Siastatin B is an effective broad-spectrum glycosidase inhibitor that can effectively inhibit the activities of sialidase, β-D-glucuronidase, N-acetyl-glucosaminidase, β-glucuronidase, and human heparinase .
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Cat. No.: HY-P2866A
CAS No.: 9012-33-3
Synonyms: NAG, Porcine kidney
Target:  

Others

Research Areas:  

Others

β-N-Acetylhexosaminidase, Porcine kidney is a glycosidase with transglycosylation activity, used to generate health-beneficial human milk oligosaccharides, and it effectively interacts with low molecular weight sugar alcohols (such as glycerol, erythritol, and xylitol). The enzyme exhibits optimal activity at pH 5 and 40 °C, and shows high thermal stability (up to 55°C) when bound to the cell wall. β-N-Acetylhexosaminidase holds promise for applications in the biotransformation of Chitin (HY-126389) and research in the food health sector .
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Cat. No.: HY-P2774
CAS No.: 9033-12-9
Synonyms: Glo-I
Target:  

Glycosidase

Research Areas:  

Inflammation/Immunology Cancer

Glyoxalase I (Glo-I) is a glycosidase and a methylglyoxal (MOG) detoxification enzyme. Glyoxalase I can be used for the research of inflammation and cancer .
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Cat. No.: HY-P2929B
CAS No.: 83534-39-8
Target:  

Glycosidase

Research Areas:  

Others

PNGase F (Immobilized, Microspin) is a resin in which PNGase F (peptide N-glycosidase F) is covalently coupled to agarose beads, and it is used to remove N-glycans from antibodies, fusion proteins and other N-glycosylated proteins. The enzyme is recombinantly expressed in Escherichia coli, with its sequence derived from Flavobacterium meningsepticum .
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Cat. No.: HY-B1610K
Sodium Citrate Buffer, 0.5M, pH 5.5 is a metal chelator and buffering agent. Sodium Citrate Buffer, 0.5M, pH 5.5 requires oxygen to participate in the oxidation process to reduce pink defects in cooked ground turkey, and it does not function via heme iron chelation or iron complex interaction. When mixed with 50% (by vol.) 1,3-dimethylimidazolium methyl sulfate, Sodium Citrate Buffer, 0.5M, pH 5.5 can serve as an aqueous buffering medium to maintain the catalytic efficiency of the hyperthermophilic β-glycosidase CelB for lactose hydrolysis at 80°C, while also acting as a reaction medium for CelB-catalyzed lactose hydrolysis and galactosyltransferase assays .
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Cat. No.: HY-145678
CAS No.: 1417906-42-3
Target:  

Glycosidase

Research Areas:  

Metabolic Disease

α-HNJNAc is a potent, competitive hexosaminidases inhibitor without interfering with other glycosidases .
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