α-HNJNAc
α-HNJNAc is a potent, competitive hexosaminidases inhibitor without interfering with other glycosidases.
For research use only. We do not sell to patients.
- CAS No.: 1417906-42-3
- Formula: C9H18N2O5
- Molecular Weight:234.25
-
Storage:
Please store the product under the recommended conditions in the Certificate of Analysis.
Biological Activity
α-HNJNAc (10, 100μM) shows no effect on GM00737 and GM01426 cell lines, but some effect on GM02931 cell line with a significant 1.8 fold activity increase. a-HNJNAc (100μM; 3 days) has no toxicity on human HL60 cell proliferation[1].
NAGLU is inhibited more efficiently by a-HNJNAc (67 μM) than by the uncorrectly configured b-HNJNAc (374 μM)[1].
MedChemExpress (MCE) has not independently confirmed the accuracy of these methods. They are for reference only.
Chemical Information
-
CAS No. 1417906-42-3
-
Molecular Weight 234.25
-
Formula C9H18N2O5
-
SMILES
CC(N[C@H]1[C@H](N[C@@H]([C@H]([C@@H]1O)O)CO)CO)=O
-
Shipping
Room temperature in continental US; may vary elsewhere.
-
Storage
Please store the product under the recommended conditions in the Certificate of Analysis.
Purity & Documentation
References
Calculators
Concentration (start) × Volume (start) = Concentration (final) × Volume (final)